 | | Vol. 11.34 – 1 September, 2022 |
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| Scientists performed scRNA-seq on 72,475 immune cells from 40 samples of tumor and matched adjacent normal tissues spanning 19 NSCLC patients, and drew a systematic immune cell transcriptome atlas.
[Signal Transduction and Targeted Therapy] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Spheroids were expanded into organoids that possessed NKX2-1+/CPM+ bud tip progenitors-like cells, which increased in number over time.
[Development] |
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| Scientists detailed a method for cryobanking of epithelial cells from either mouse or human lung tissue for preservation of their phenotypic and functional characteristics.
[American Journal of Respiratory Cell and Molecular Biology] |
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| Researchers found that alveolar progenitors in organoid culture in vitro showed phenotypic lineage plasticity as they could yield alveolar or bronchial cell-type progeny.
[Communications Biology] |
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| The authors determined the exact role of the irreversible FGFR1-4 inhibitor FIIN-2 in lung adenocarcinoma and to clarify its underlying molecular mechanisms.
[Cell Death & Disease] |
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| In vitro and in vivo studies showed that Palladin promoted stem cell-like properties, including cell viability, invasion, migration, self-renewal abilities, taxol resistance, and tumorigenicity.
[Cancer Medicine] |
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| Investigators discuss the important role of macrophages and lung alveolar epithelial cells in the progression of acute respiratory distress syndrome (ARDS).
[Inflammation] |
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| To explore the feasibility of the clinical application of radiomics in predicting PD-L1 expression, immunotherapy response, and long-term prognosis, the authors review and summarize recently published works in NSCLC.
[Thoracic Cancer] |
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| A complex mix of politics, economics and shifting career priorities has made it hard for principal investigators to recruit new lab members.
[Nature News] |
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| November 13 – 18, 2022
Ventura, California, United States |
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| | Helmholtz Munich – Neuherberg, Germany |
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| | University of California San Francisco – San Francisco, California, United States |
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| | STEMCELL Technologies, Inc. – Vancouver, British Columbia, Canada |
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| | Stanford Medicine – Stanford, California, United States |
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| | NYU Langone Health – New York, New York, United States |
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