 | | Vol. 11.45 – 17 November, 2022 |
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| Investigators identified B cell lymphoma 6 (BCL6) as a lynchpin in KRAS-driven lung cancer, revealing a crucial role of BCL6 in promoting KRAS-addicted lung cancer and suggested BCL6 as a therapeutic target for the treatment of this intractable disease.
[Journal of Clinical Investigation] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| To study the function of transient receptor potential ankyrin 1 (TRPA1) in transforming growth factor β1 (TGF-β1)-driven fibroblast to myofibroblast differentiation and the development of pulmonary fibrosis, TRPA1 expression and function were analyzed in cultured primary human lung fibroblasts.
[American Journal of Respiratory Cell and Molecular Biology] |
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| Investigators analyzed the contribution of IL-11 to pulmonary hypertension in patients with idiopathic pulmonary fibrosis and the potential mechanisms implicated.
[Respiratory Research] |
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| Researchers investigated whether Raf kinase inhibitor protein (RKIP) regulated the inflammatory response via the ERK/MAPK pathway.
[International Journal of Molecular Medicine] |
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| Scientists investigated whether O2 concentration affected the response of mitochondria to X-rays radiation, which was associated with tumor microenvironment formation via fibroblast activation in radiation-related tumors.
[International Journal of Radiation Biology] |
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| Researchers verified that SNORD88C was up-regulated in tissue and plasma and served as a non-invasive diagnostic biomarker. They confirmed that SNORD88C promoted proliferation and metastasis of NSCLC in vitro and in vivo.
[Cell Death & Differentiation] |
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| Investigators tested whether ligand-independent activation of EphA2 modulated chemoresistance by enhancing stemness in SCLC.
[Cancer Science] |
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| Scientists analyzed the expression of KvS subfamilies in human lung tumors and identified that potassium voltage-gated channel subfamily F member 1 (KCNF1) was up-regulated in NSCLC.
[Cancer Gene Therapy] |
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| Researchers explored the role and mechanism of circ_0079530 in NSCLC progression.
[Histology and Histopathology] |
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| The authors summarize the mechanisms of chemoresistance of cancer stem cells in SCLC and the latest advances in targeted therapies.
[Seminars in Cancer Biology] |
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| Apollomics Inc. announced that the FDA has granted Orphan Drug Designation to vebreltinib (APL-101) for the treatment of NSCLC with MET genomic tumor aberrations.
[Apollomics, Inc.] |
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| Shanghai Junshi Biosciences Co., Ltd. announced that the company has submitted a marketing authorization application to the European Medicines Agency for toripalimab for the treatment of nasopharyngeal carcinoma and esophageal squamous cell carcinoma.
[Shanghai Junshi Biosciences Co., Ltd. (GlobeNewswire)] |
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| April 6 – April 8
Estoril, Portugal |
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| | STEMCELL Technologies, Inc. – Boston, Massachusetts, United States |
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| | Baylor College of Medicine – Austin, Texas, United States |
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| | Yale University – New Haven, Connecticut, United States |
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| | Boston University – Boston, Massachusetts, United States |
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| | Imperial College London – London, England, United Kingdom |
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Cancer Stem Cell News
Cell Therapy News
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ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
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Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
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Pancreatic Cell News
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Pulmonary Cell News
