 | | Vol. 12.08 – 2 March, 2023 |
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| Scientists reported a screening platform to test the antiviral efficacy of a natural product library against SARS-CoV-2 and verify their activity using lung organoids.
[Biomaterials Research] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| In vitro, single-walled carbon nanotube exposure resulted in profound dysfunctions of MLE-12 cells, characterized by impaired autophagic flux and accelerated cellular senescence.
[Journal Of Nanobiotechnology] |
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| The molecular mechanisms of the innate immune response, regulated by Pellino3, were investigated in lung epithelial cells during influenza B virus infection.
[Immunology] |
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| Researchers tested the effects of nicotine aerosols from electronic cigarettes in primary human bronchial epithelial cells, followed by in vitro and in vivo electrophysiologic assays for cystic fibrosis transmembrane conductance regulator (CFTR) activity.
[American Journal Of Physiology-Lung Cellular And Molecular Physiology] |
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| A reinforcement material consisting of carbon rods, carbon concrete composite, and thermally treated carbon concrete was physicochemically and toxicologically analyzed in monocultured lung epithelial cells and co-cultured lung epithelial cells and fibroblasts at the air-liquid interface.
[Environmental Toxicology And Pharmacology] |
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| | Scientists found that Homeobox C11 (HOXC11) overexpressed in lung adenocarcinoma and was associated with worse overall survival. Moreover, its expression in lung cancer was regulated by IκB kinase α, a pivotal kinase in NF-κB signaling, which was related to the ubiquitination of HOXC11.
[Cell Death & Disease] |
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| Investigators demonstrated that extrinsic 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) treatment induced apoptosis and increased DNA damage in EGFR-mutant lung cancer cell lines.
[British Journal Of Cancer] |
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| Scientists transplanted lung cancer cell lines and cell line-derived organoids into a chorioallantoic membrane to investigate angiogenesis and invasion.
[Cancer Cell International] |
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| Researchers investigated the effects of P2X7 receptors on A549 cell migration and invasion and revealed the molecular mechanisms mediated by it.
[Purinergic Signalling] |
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| The authors review how the implementation of 3D organoid technology into tumor microenvironment-modeling platforms might facilitate the exploration of macrophage-targeted therapies in non-small cell lung cancer immunotherapeutic research.
[Elife] |
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| LIfT BioSciences entered into a development and manufacturing partnership for N-LIfT, LIfT’s first-in-class neutrophil progenitor based Leukocyte Infusion Therapy for the treatment of various cancer indications, including Pancreatic Cancer, Lung Cancer, and other solid tumors.
[LIfT Biosciences ] |
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| March 15 – 18, 2023
Denver, Colorado, United States |
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| | University of California, San Francisco – San Francisco, California, United States |
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| | University of Virginia – Charlottesville, Virginia, United States |
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| | University of Louisville – Louisville, Kentucky, United States |
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| | STEMCELL Technologies – Vancouver, British Columbia, Canada |
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| | IRCCS Candiolo Cancer Institute – Turin, Italy |
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