 | | Vol. 12.15 – 20 April, 2023 |
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| Researchers found that SMAD7, a direct downstream transcriptional target and also a key antagonist of TGF-β signaling, was transcriptionally suppressed in lung adenocarcinoma due to DNA hypermethylation.
[Cell Discovery] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists devised a strategy to deliver the membrane-bound wingless-type MMTV integration site family, member 3A (Wnt3a) over a long distance by anchoring it to the surface of extracellular vesicles.
[Advanced Science] |
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| Investigators developed a transwell system in which airway organoid–derived differentiated human lung epithelial cells were co-cultured with primary human lung microvascular endothelial cells.
[Life Science Alliance] |
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| Researchers explored whether exosomes and prostaglandin-endoperoxide synthase 2 (PTGS2)/PGE2 signaling pathway affected COPD by influencing the ferroptosis of bronchial epithelial cells by constructing a model of COPD.
[Scientific Reports] |
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| Scientists assessed the membrane topographical and structural effects of PM2.5 from incense PM2.5 exposure in real time on A549 lung carcinoma epithelial cells and SH-SY5Y neuroblastoma cells that had been fixed to preclude adaptive cell responses.
[Analytical And Bioanalytical Chemistry] |
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| Investigators developed murine alleles of the KEAP1 and NRF2 mutations found in human NSCLC and comprehensively interrogated their impact on tumor initiation and progression.
[Cancer Research] |
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| Researchers investigated the efficacy of a single MET inhibitor in EGFR-mutant, MET-amplified lung cancer cells and the matched clinical cases and patient-derived cells.
[British Journal Of Cancer] |
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| Scientists tested whether ionizing radiation treatment along with 3,3′-diselenodipropionic acid, a redox-active organodiselenide achieved better tumor control by suppressing the growth and migration of lung cancer cells.
[IUBMB Life] |
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| Investigators explored the role and underlying mechanism of circ_PLXND1 in NSCLC progression. Circ_PLXND1 and ERBB3 were upregulated while miR-1287-5p was downregulated in NSCLC tissues and cells.
[Thoracic Cancer] |
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| The authors provide a review of the oncogenic role of the most relevant molecular alterations in NSCLC and emerging treatments in this setting beyond epidermal growth factor receptor (EGFR)-driven and anaplastic lymphoma kinase (ALK)-driven diseases.
[Cancer] |
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| The company was accused of unfair, deceptive acts or practices in the advertising and marketing of Juul products in the state, specifically targeting teenagers. The lawsuit claimed Juul targeted these users through social media, influencer marketing, and fashion bloggers and celebrities popular with teenagers.
[CNN Business] |
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| April 23 – 26, 2023
Snowbird, Utah, United States |
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| | Indiana University – Indiana, Pennsylvania, United States |
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| | Case Western Reserve University – Cleveland, Ohio, United States |
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| | University of Liverpool – Liverpool, England, United Kingdom |
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| | STEMCELL Technologies, Inc. – Vancouver, British Columbia, Canada |
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| | Medical College of Wisconsin – Milwaukee, Wisconsin, United States |
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