| Vol. 12.48 – 7 December, 2023 |
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| Scientists studied the impact of the apolipoprotein B mRNA-editing catalytic subunit-like (APOBEC) enzyme APOBEC3B on epidermal growth factor receptor-driven lung cancer. [Nature Genetics] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| Following intratracheal aerosol delivery of Cy5-labeled peptide in rhesus macaques, the authors confirmed delivery throughout the respiratory tract. [Nature Communications] |
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| K329R knockin mice with defective RBM47-ISGylation displayed heightened susceptibility to LPS-induced acute lung injury and lung tumorigenesis. [Cell Death Discovery] |
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| Human alveolar epithelial cells and macrophages were exposed in vitro to dust and assessed for cytotoxicity and inflammation. [Respirology] |
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| The angiotensin (Ang)-(1–7)-/Mas axis inhibited TGF-β1-induced lung fibroblast differentiation, inflammation, and fibrosis in bleomycin-treated lung tissue. [European Journal Of Pharmacology] |
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| The authors investigated the biological effects of chemically characterized indoor dust extracts using three-dimensional lung cancer cell cultures combining phenotypic and lipidomic analyses. [Environmental Science & Technology] |
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| Elevated USP13 promoted KRAS-mutant NSCLC metastasis, which was associated with poor prognosis in NSCLC patients. [Cell Reports] |
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| The binding targets and underlying mechanisms of the differentially expressed miRNAs were verified by in vitro and in vivo experiments. [Cell Death & Disease] |
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| The in vitro cytotoxicity of the 17 semisynthesized derivatives of renieramycin S against human NSCLC cells in parallel with normal cell lines was evaluated. [Scientific Reports] |
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| The roles and importance of extracellular vesicles substantially differs between studies, depending on experimental conditions and parent cell origins of extracellular vesicles that modify the nature of their cargo. [Journal Of Nanobiotechnology] |
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| The therapy is a bispecific antibody targeting EGFR and c-MET, which are believed to be dysregulated in many tumors such as NSCLC. [Fierce Biotech] |
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| January 22 – 25, 2024 Santa Fe, New Mexico, United States |
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| Cedars-Sinai – Los Angeles, California, United States |
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| University of California, San Francisco – San Francisco, California, United States |
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| Indiana University – Indiana, Pennsylvania, United States |
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| Rutgers Health – Newark, New Jersey, United States |
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| Royal College of Surgeons in Ireland – Dulin, Ireland |
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