 | | Vol. 13.00 – 4 January, 2024 |
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| Researchers presented a human apical-out airway organoid using a biochemically defined hybrid hydrogel system.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators revealed that placenta-expressed transcript 1 (Plet1) was released from alveolar macrophages, and acted as important mediator of macrophage-epithelial cross-talk during lung repair by inducing proliferation of alveolar epithelial cells and re-sealing of the epithelial barrier.
[Nature Communications] |
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| Scientists investigated IPF dysregulated cross-talk, primary normal human bronchial epithelial cells and primary normal human lung fibroblasts or diseased human lung fibroblasts from IPF patients, were co-cultured in direct contact at the air–liquid interface.
[Scientific Reports] |
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| The authors identified ncRNA-related ceRNA networks and investigated the role of the Wnt/β-catenin pathway in pulmonary fibrosis. Male Wistar rats were intratracheally instilled with 0.015, 0.06, and 0.24 mg/kg NiONPs twice a week for nine weeks.
[Environmental Toxicology] |
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| Adenosine receptor activities in NSCLC cells were monitored in real-time with high sensitivity through a carbon nanotube field-effect transistor (CNT-FET). In this method, they hybridized a CNT-FET with NSCLC cells expressing A2A and A2B adenosine receptors to construct a hybrid platform.
[ACS Applied Materials & Interfaces] |
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| Non-metabolic function of phosphoglycerate kinase 1 (PGK1) in NSCLC was explored by integrating bioinformatics analyses, cellular experiments, and nude mouse xenograft models.
[Biology Direct] |
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| Clinical data along with associated mRNA expression profiles from LUAD cases were collected in TCGA and GEO databases. 13 immunogenic cell death (ICD)-related genes were identified. Relations of ICD-related gene expression with prognosis of patients, and tumor immune microenvironment were analyzed.
[Cell Cycle] |
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| Researchers demonstrated the effects of SF3B4 in lung adenocarcinoma (LUAD) via apoptosis, proliferation, migration assays, etc. Gene manipulations confirmed the role of SF3B4 via KAT2A. SF3B4 was found to promote LUAD growth.
[Scientific Reports] |
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| Scientists investigated the aberrant expression of histone H3-H4 chaperone anti-silencing function 1 (ASF1B) in lung adenocarcinoma and its potential link to patient survival using multiple databases.
[Journal Of Cancer] |
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| The authors discuss different human regulatory B cell (Bregs) subsets, several ways of Breg induction, as well as the mechanisms through which they exert immunoregulatory functions, and their role in childhood allergic asthma.
[Molecular and Cellular Pediatrics] |
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| The expected price hikes come as the pharmaceutical industry gears up for the Biden Administration to publish significantly discounted prices for 10 high-cost drugs in September, and continues to contend with higher inflation and manufacturing costs.
[Reuters] |
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| February 22 – 24, 2024
Austin, Texas, United States |
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| | Human Technopole – Location |
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| | Guangzhou Institutes of Biomedicine and Health – Guangzhou, China |
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| | University of Melbourne – Melbourne, Australia |
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| | University of California, San Francisco – San Francisco, California, United States |
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| | Rutgers Health – Newark, New Jersey, United States |
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