 | | Vol. 13.01 – 11 January, 2024 |
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| Through a curated CRISPR-based screen of RNA Helicases, the authors identified DExD/H-box helicase 9 (DHX9) as a potent repressor of double-stranded RNA in small cell lung cancers.
[Cancer Discovery] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers analyzed expression levels of interleukin-33 (IL33) in the epithelial cells from the lung of house dust mites-challenged mice depending on inhalation of interferon-λ.
[Allergy] |
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| Investigators showed that Sox2 preserved airway cell identity and prevented fate changes into either functional alveolar tissue or pathological keratinization following lung injury.
[NPJ Regenerative Medicine] |
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| By using cultured idiopathic pulmonary fibrosis (IPF) patient-derived alveolar basal cells, the authors aimed to establish an in vitro– and in vivo model to mimic Honeycomb cysts formation in IPF.
[Respiratory Research] |
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| Scientists exposed lung fibroblast and epithelium to Air, propylene glycol/vegetable glycerine, menthol flavored, or tobacco-flavored e-cig, and determined the cytotoxicity, inflammation, and wound healing ability in 2D cells and 3D microtissue chip models.
[Respiratory Research] |
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| Investigators showed that in GSEA analysis of TCGA lung adenocarcinoma RNA-seq data, the Kelch-like ECH-associated protein 1 (KEAP1) mutations in R320 and R470 were associated with enhanced Tumor Necrosis Factor alpha (TNFα) – Nuclear Factor kappa subunit B signaling, and MYC and MTORC1 pathways.
[Redox Biology] |
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| Protein tyrosine phosphatase receptor type O (PTPRO) decreased lung adenocarcinoma migration and invasion by regulating proteins involved in the epithelial-to-mesenchymal transition.
[Cell Death & Disease] |
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| Researchers utilized well-characterized KrasG12D-driven non-small cell lung cancer mouse model to investigate the role of Mediator complex subunit 23 (MED23) in lung cancer.
[British Journal Of Cancer] |
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| An integrated strategy with excellent accuracy and high throughput was proposed for the precise indication of single nucleotide polymorphism in nonsmall cell lung cancer diseases.
[Analytical Chemistry] |
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| The authors review evolving knowledge about the extracellular matrix’s role in homeostasis and disease in the lung.
[American Journal Of Respiratory Cell And Molecular Biology] |
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| Researchers hope some of the first rigorous placebo-controlled clinical trials of possible Long Covid treatments will report outcomes, though they may be preliminary.
[Science] |
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| February 23 – 26, 2024
Washington, DC, United States |
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| | University of Illinois at Chicago College of Medicine – Chicago, Illinois, United States |
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| | Princeton University – Princeton, New Jersey, United States |
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| | University of Cambridge – Cambridge, England, United Kingdom |
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| | Human Technopole – Milan, Italy |
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| | Guangzhou Institutes of Biomedicine and Health – Guangzhou, China |
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Cancer Stem Cell News
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