| Vol. 14.18 – 12 May, 2022 |
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A Genome-Wide CRISPR-Cas9 Knockout Screen Identifies Essential and Growth-Restricting Genes in Human Trophoblast Stem Cells | The authors utilized a genome-wide CRISPR-Cas9 knockout screen to comprehensively identify essential and growth-restricting genes in human trophoblast stem cells. [Nature Communications] |
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PUBLICATIONSRanked by the impact factor of the journal |
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Induction of Human Trophoblast Stem-Like Cells from Primed Pluripotent Stem Cells | Scientists reported that trophoblast stem-like cells could be generated from human primed pluripotent stem cells by a short-term treatment of bone morphogenetic protein 4 without amnion lineage marker expression. [Proceedings of the National Academy of Sciences of the United States of America] |
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Molecular Regulation of Trophoblast Stem Cell Self-Renewal and Giant Cell Differentiation by the Hippo Components YAP and LATS1 | Trophoblast giant cell differentiation was associated with cytoplasmic retention of YAP, heightened pYAPSer127, decrease in the level of the core Hippo component, LATS1, which thereby impeded LATS1-LIMK2 association. [Stem Cell Research & Therapy] |
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Improved Outcomes of Single-Unit Cord Blood Transplantation for Acute Myeloid Leukemia by Killer Immunoglobulin-Like Receptor 2DL1-Ligand Mismatch | To investigate their role in acute myeloid leukemia, mismatch of KIR2DL1, KIR3DL1, and KIR3DL2-ligand were retrospectively assessed in patients undergoing cord blood transplantation with graft-versus-host disease prophylaxis comprising a calcineurin inhibitor plus methotrexate or mycophenolate mofetil. [Bone Marrow Transplantation] |
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Conditioned Medium from Amniotic Fluid Mesenchymal Stem Cells Could Modulate Alzheimer’s Disease-Like Changes in Human Neuroblastoma Cell Line SY-SY5Y in a Paracrine Manner | Researchers investigated the paracrine effect of amniotic fluid-derived mesenchymal stem cells on Alzheimer’s disease changes in human SH–SY5Y cells. [Tissue and Cell] |
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Overexpression of lncRNA HCP5 in Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Promoted the Proliferation and Inhibited the Apoptosis of Ovarian Granulosa Cells via the Musashi RNA-Binding Protein 2/Oestrogen Receptor Alpha 1 Axis | Human umbilical cord MSC-derived exosomes promoted the proliferation of ovarian granulosa cells and estrogen receptor alpha 1 expression and inhibited cell apoptosis. [Endocrine Journal] |
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Umbilical Hernia Repair in Patients with Cirrhosis: Who, When and How to Treat | Scientists provide an overview of crucial elements in the treatment of patients with cirrhosis and umbilical hernia. [Hernia] |
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Therapeutic Solutions International Announces Launching of Phase III Clinical Trial for Treating COVID-19 Lung Damage Using Its JadiCell™ Universal Donor Stem Cell Drug | Therapeutic Solutions International, Inc. announced filing of an IND and FDA seeking permission to treat 10 patients with advanced COPD using its universal donor adult stem cell product termed “JadiCell™”. [Therapeutic Solutions International, Inc. (BioSpace)] |
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| June 9 – 12, 2022 Vienna, Austria & Online |
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| Harvard Medical School – Boston, Massachusetts, United States |
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| Luna Genetics, Inc. – Houston, Texas, United States |
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| New York University College of Dentistry – New York, New York, United States |
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| The University of Iowa – Iowa City, Iowa, United States |
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| University of Gothenburg – Gothenburg, Sweden |
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