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Pulmonary Cell NewsAll Articles by Author:
Britya Ghosh
Cancer Stem Cell News
Disruption of β-Catenin-Mediated Negative Feedback Reinforces cAMP-Induced Neuronal Differentiation in Glioma Stem Cells
[Cell Death & Disease] Scientists demonstrated that cAMP triggered neuronal differentiation and compromised the self-renewal capacity in glioma stem cells.
Cancer Stem Cell News
GSK3β Palmitoylation Mediated by ZDHHC4 Promotes Tumorigenicity of Glioblastoma Stem Cells in Temozolomide-Resistant Glioblastoma through the EZH2–STAT3 Axis
[Oncogenesis] Researchers found that GSK3β was noted as a substrate for ZDHHC4-mediated palmitoylation at the Cys14 residue, which enhanced glioblastoma temozolomide resistance and glioblastoma stem cell self-renewal.
Cancer Stem Cell News
ΔNp63α Mediates Sulforaphane Suppressed Colorectal Cancer Stem Cell Properties through Transcriptional Regulation of Nanog/Oct4/Sox2
[Journal of Nutritional Biochemistry] Scientists showed that ΔNp63α expression was enhanced in sphere-forming colorectal cancer cells.
Cancer Stem Cell News
Identification of Two Cancer Stem Cell-Like Populations in Triple-Negative Breast Cancer Xenografts
[Disease Models & Mechanisms] The multiple-microtissue transcriptome analysis revealed three cancer cell-type clusters in the primary tumor and axillary lymph node metastasis, two of which were CSC-like clusters.
Cancer Stem Cell News
GM-CSF-miRNA-Jak2/Stat3 Signaling Mediates Chemotherapy-Induced Cancer Cell Stemness in Gastric Cancer
[Frontiers in Pharmacology] Researchers treated two human gastric cancer cell lines SGC7901 and BGC823 with 5-Fluorouracil or Cisplatin in vitro.
Cancer Stem Cell News
Recombinant Expression a Novel Fibronectin—Collage Fusion Peptide Modulating Stem Cell Stemness via Integrin β3
[Applied Microbiology and Biotechnology] A novel recombinant protein fibronectin-collagen peptide was designed to modulate the function of extracellular matrix expressed by Picha. pastoris strain X33.
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CAR Affinity Modulates the Sensitivity of CAR-T Cells to PD-1/PD-L1-Mediated Inhibition
[Nature Communications] The authors interrogated CAR-T cells targeting HER2 with either low or high affinity in various preclinical models.
Emx2 Underlies the Development and Evolution of Marsupial Gliding Membranes
[Nature] By combining epigenomics, transcriptomics and in-pouch marsupial transgenics, scientists showed that Emx2 was a critical upstream regulator of patagium development.
Designing Biomimetic 3D-Printed Osteochondral Scaffolds for Enhanced Load-Bearing Capacity
[Tissue Engineering Part A] Cmputational simulations revealed that interfacial fibrils within a bilayer alter osteochondral scaffold deformation patterns by redirecting load-induced stresses toward the top of the cartilage layer.
