Umbilical & Placental Cell News Volume 14.24 | Jun 30 2022

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    Vol. 14.24 – 30 June, 2022
    TOP STORY

    An Optimized Method for Obtaining Clinical-Grade Specific Cell Subpopulations from Human Umbilical Cord-Derived Mesenchymal Stem Cells

    Scientists established a general operation process for obtaining high-quality clinical-grade cell subpopulations from human umbilical cord MSCs based on particular markers.
    [Cell Proliferation]
    Full Article
    Facts Vs. claims. Three scientists peer reviewed a life science vendor to get to the truth. See for yourself.
    PUBLICATIONSRanked by the impact factor of the journal

    Controllable Manipulation of Alginate-Gelatin Core-Shell Microcarriers for HUMSCs Expansion

    Researchers studied the attachment and proliferation of human umbilical cord-MSCs (HUMSCs) on alginate-gelatin core-shell microcarriers with different mechanical strengths modulated by gelatin coating, and the harvested cells were characterized to verity their differentiation potential.
    [International Journal of Biological Macromolecules]
    Full Article

    Wharton’s Jelly Mesenchymal Stem Cell-Derived Small Extracellular Vesicles as Natural Nanoparticles to Attenuate Cartilage Injury via microRNA Regulation

    Investigators identified natural small extracellular vesicles harvested from Wharton’s jelly MSCs.
    [International Journal of Pharmaceutics]
    Full ArticleGraphical Abstract

    Outcome of Human Umbilical Cord Blood Stem Cell Transplantation (CBT) for Acute Myeloid Leukemia in Patients Achieving First Complete Remission after One versus Two Induction Courses: A Study From the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT)

    Researchers compared transplantation outcomes of adult patients with acute myeloid leukemia that underwent CBT in CR1 following one versus two induction courses.
    [Bone Marrow Transplantation]
    Abstract

    Long Noncoding RNA PVT1 Accelerates the Growth of Placental Trophoblasts in Preeclampsia through the microRNA-24-3p/HSD11B2 Axis

    Plasmacytoma variant translocation 1 (PVT1), miR-24-3p, and HSD11B2 expression levels in normal placental tissues and preeclampsia placental tissues were defined.
    [Molecular Reproduction and Development]
    Abstract

    Comparison of Biological Characteristics of Human Adipose- and Umbilical Cord- Derived Mesenchymal Stem Cells and Their Effects on Delaying the Progression of Osteoarthritis in a Rat Model

    Umbilical cord-derived-MSCs and adipose-derived-MSC were isolated from the umbilical cord and subcutaneous fatty tissue of humans respectively and identified by flow cytometry.
    [Acta Histochemica]
    Full Article
    ON987CXN-jul-728x90-2022
    REVIEWS

    Modeling Human Placental Villous Development: Designing Cultures That Reflect Anatomy

    The authors outline the current understanding of placental development, and critically consider the range of established and emerging culture models used to study this, with a focus on those derived from primary tissue.
    [Cellular and Molecular Life Sciences]
    Full Article
    INDUSTRY AND POLICY NEWS

    BioRestorative Therapies Announces First Patient Enrolled for the Company’s Phase II Clinical Trial to Treat Chronic Lumbar Disc Disease (cLDD)

    BioRestorative Therapies, Inc. announced that the first patient has been enrolled in the company’s Phase II clinical trial evaluating the safety and preliminary efficacy of BRTX-100, an autologous bone marrow-derived mesenchymal stem cell targeting chronic lumbar disc disease.
    [BioRestorative Therapies, Inc. (GlobeNewswire, Inc.)]
    Press Release
    FEATURED EVENT

    Advances in Therapeutic Applications of Stem Cells

    December 8 – 10, 2022
    Los Angeles, California, United States

    > See All Events

    JOB OPPORTUNITIES

    Clinical Cell Therapy Associate – Cord Blood Bank

    University of Texas MD Anderson Cancer Center – Houston, Texas, United States

    Senior Research Assistant – Umbilical Vein Endothelial Cells

    University of Texas MD Anderson Cancer Center – Houston, Texas, United States

    Postdoctoral Scientist – Cardiovascular Magnetic

    Boston Children’s Hospital – Boston, Massachusetts , United States

    Postdoctoral Fellow – Immunology, Epigenetics, and Cellular Metabolism

    Van Andel Institute – Grand Rapids, Michigan, United States

    Postdoctoral Position – Computational Neurobiology

    Flanders Institute for Biotechnology – Antwerp, Belgium

    > See All Jobs

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