Umbilical & Placental Cell News Volume 14.26 | Jul 14 2022

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    2022-07-14 | UPCN 14.26


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    Vol. 14.26 – 14 July, 2022
    TOP STORY

    Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Attenuate Myocardial Infarction Injury via miR-24-3p-Promoted M2 Macrophage Polarization

    Investigators explored the effects of human umbilical cord MSC-derived exosomes on macrophage polarization and their roles in cardiac repair after myocardial infarction
    [Advanced Biology]

    Abstract
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    PUBLICATIONSRanked by the impact factor of the journal

    Conditioned Medium of Amniotic Fluid-Derived Stromal Cells Exerts a Bone Anabolic Effect by Enhancing Progenitor Population and Angiogenesis

    In an in vitro culture experiment, amniotic fluid-derived stromal cells increased osteoclast differentiation of bone marrow-derived macrophages, but had no significant effect on the osteogenic differentiation of preosteoblasts.
    [Journal of Tissue Engineering and Regenerative Medicine]

    Abstract

    The Human Amniotic Epithelium Confers a Bias to Differentiate toward the Neuroectoderm Lineage in Human Embryonic Stem Cells

    The authors proposed that the interaction of human embryonic stem cells (hESC) with human amniotic epithelial cells confered hESC a biased potential that resembled the anteriorized epiblast.
    [Developmental Biology]

    Abstract

    Regionally Distinct Trophoblast Regulate Barrier Function and Invasion in the Human Placenta

    Researchers used single cell RNA sequencing to compare the cell types and molecular programs between these two regions in the second trimester human placenta.
    [Developmental Biology]

    Abstract

    Cord Blood Antimicrobial Peptide LL37 Levels in Preterm Neonates and Association with Preterm Complications

    Little is known about the regulation of human cord blood LL37 in preterm neonates and the association with preterm complications. Scientists investigated the concentration of LL37 in cord blood of preterm infants and correlation with preterm complications.
    [Italian Journal of Pediatrics]

    Full Article
    Survey results on the needs and challenges in the human pluripotent stem cell field
    REVIEWS

    Mesenchymal Stem Cell–Derived Extracellular Vesicles as an Advanced Therapy for Chronic Wounds

    The authors review the evidence demonstrating that MSC-extracellular vesicles target the processes leading to chronic wounds.
    [Cold Spring Harbor Perspectives in Biology]

    Abstract

    From Decidualization to Pregnancy Progression: An Overview of Immune and Metabolic Effects of VIP

    Scientists overview critical aspects of embryo implantation and placental development with special focus on the immune and metabolic role of the vasoactive intestinal peptide expressed by decidual and trophoblast cells.
    [American Journal of Reproductive Immunology]

    Abstract
    INDUSTRY AND POLICY NEWS

    Professor Rachel West Honored with KY CHA Award in Stem Cell Technology

    The American Society of Reproductive Medicine honored Professor Rachel West at Auburn University with the KY CHA Award in Stem Cell Technology for her contributions to the development of reproductive medicine.
    [Business Wire, Inc.]

    Press Release
    FEATURED EVENT

    Till & McCulloch Meetings

    October 3 – 5, 2022
    Vancouver, British Columbia, Canada

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    JOB OPPORTUNITIES

    Associate Professor – Thematic Research Programs

    The Chinese University of Hong Kong – Hong Kong, China

    Postdoctoral Research Fellow – Neural Stem Cells

    University of Rochester Medical Center – Rochester, New York, United States

    Postdoctoral Scientist – Cardiovascular Magnetic

    Boston Children’s Hospital – Boston, Massachusetts , United States

    Postdoctoral Fellow – Immunology, Epigenetics, and Cellular Metabolism 

    Van Andel Institute – Grand Rapids, Michigan, United States

    Postdoctoral Position – Computational Neurobiology

    Flanders Institute for Biotechnology – Antwerp, Belgium

    > See All Jobs

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