Umbilical & Placental Cell News Volume 14.27 | Jul 21 2022

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    2022-07-21 | UPCN 14.27


    Umbilical-and-Placental-Cell-News-email-header (1)
    Vol. 14.27 – 21 July, 2022
    TOP STORY

    Pentoxifylline as a Therapeutic Option for Preeclampsia: A Study on Its Placental Effects

    The authors investigated the placental transfer, vascular effects, and anti-inflammatory capacity of pentoxifylline in healthy and preeclamptic human placentas.
    [British Journal of Pharmacology]

    Abstract
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    UC-MSCs Promote Frozen-Thawed Ovaries Angiogenesis via Activation of the Wnt/β-Catenin Pathway In Vitro Ovarian Culture System

    Researchers established an in vitro ovarian culture system to restore frozen-thawed ovarian function before transplantation with the application of umbilical cord (UC)-MSCs.
    [Stem Cell Research & Therapy]

    Full Article

    Human Umbilical Cord Blood-Derived MSCs Trans-Differentiate into Endometrial Cells and Regulate Th17/Treg Balance through NF-κB Signaling in Rabbit Intrauterine Adhesions Endometrium

    Scientists investigated the effects and underlying mechanism of human umbilical cord blood-derived MSCs on the endometrial reconstruction after transplantation.
    [Stem Cell Research & Therapy]

    Full Article

    Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Regulate Lymphangiogenesis via the miR-302d-3p/VEGFR3/AKT Axis to Ameliorate Inflammatory Bowel Disease

    Researchers investigated the therapeutic effect of human umbilical cord MSC-derived exosomes in a mouse model of inflammatory bowel disease during the modulation of lymphangiogenesis.
    [International Immunopharmacology]

    Abstract

    A Hybrid Hydrogel Encapsulating Human Umbilical Cord Mesenchymal Stem Cells Enhances Diabetic Wound Healing

    Investigators constructed a hydrogel with low toxicity and adjustable mechanical properties from gelatin methacrylate and chitosan-catechol, and encapsulated human umbilical cord-MSCs.
    [Journal of Materials Science-Materials in Medicine]

    Full ArticleGraphical Abstract

    Noninvasive Autologous Mitochondria Transport Improves the Quality and Developmental Potential of Oocytes from Aged Mice

    Murine umbilical cord MSCs were isolated from a female pup and cryopreserved. After the female aged, its germinal vesicle oocytes were collected and treated to weaken the zona pellucida.
    [F&S Science]

    Abstract
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    REVIEWS

    TA-MSCs, TA-MSCs-EVs, MIF: Their Crosstalk in Immunosuppressive Tumor Microenvironment

    The authors summarize the main effects and related mechanisms of tumor-associated (TA) MSCs, TA-MSCs-derived extracellular vesicles (MSCs-EVs), and migration inhibitory factor (MIF) on tumors, and describe their relationships.
    [Journal of Translational Medicine]

    Full Article
    INDUSTRY AND POLICY NEWS

    Antengene Announces Research Collaboration with Celularity to Evaluate the Potential Therapeutic Synergy of Combining Antengene’s Best-in-Class Bispecific Antibody with Celularity’s Natural Killer Cell Platform

    Antengene Corporation Limited announced that it has entered into a pre-clinical research collaboration with Celularity Inc., a clinical-stage biotechnology company developing placental-derived allogeneic cell therapies.
    [Antengene Corporation Ltd (Cision US Inc.)]

    Press Release
    FEATURED EVENT

    GISM Annual Meeting 2022

    October 20 – 21, 2022
    Turin, Italy

    > See All Events

    JOB OPPORTUNITIES

    Postdoctoral Position – Combined Omics

    UT Health Science Center at San Antonio – San Antonio, Texas, United States

    Clinical Cell Therapy Associate – Cord Blood Bank Program

    University of Texas MD Anderson Cancer Center – Houston, Texas, United States

    Postdoctoral Researcher – Microfluidics, Organoids, and Precision Medicine

    Lehigh University – Bethlehem, Pennsylvania, Untied States

    Associate Professor – Thematic Research Programs

    The Chinese University of Hong Kong – Hong Kong, China

    Postdoctoral Research Fellow – Neural Stem Cells

    University of Rochester Medical Center – Rochester, New York, United States

    > See All Jobs

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