 | | Vol. 14.28 – 28 July, 2022 |
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| An acute graft-versus-host disease model (aGVHD) was established to observe the therapeutic effects of extracellular vesicles from mesenchymal stromal cell-derived human umbilical cords (hUC-EVs)-arsenic trioxides (ATOs) on aGVHD.
[Journal of Hematology & Oncology] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators performed single-cell profiling of more than 16,160 cells to construct a dynamic molecular landscape of human megakaryopoiesis from cord blood hematopoietic stem/progenitor cells, which enabled them to uncover cellular heterogeneity and unique features of neonatal megakaryocytes.
[Stem Cells Translational Medicine] |
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| To clarify how human umbilical cord (hUC)-derived MSCs worked on skin aging, scientists employed a skin-aging model of human dermal fibroblasts to conduct in vitro assays by applying a conditional medium of hUCMSCs.
[Stem Cell Reviews and Reports] |
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| Exosome mimetic vesicles from human umbilical cord (hUC) MSCs were isolated by continuous extrusion, and exosomes were identified after hUC MSC ultracentrifugation.
[Stem Cell Research & Therapy] |
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| Researchers investigated the role of miR-126-3p-modified human umbilical cord MSCs derived exosomes on the treatment of premature ovarian failure.
[Stem Cell Research & Therapy] |
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| Foreskin MSCs (FSMSCs) and human umbilical cord MSCs (HuMSCs) were isolated and cultured until the third passage. When cocultured with LPS pretreated peripheral blood mononuclear cells, FSMSCs and HuMSCs could effectively reduced the secretion of IL-1β and TNF-α.
[Cell & Bioscience] |
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| The authors investigated whether human umbilical cord-derived MSC intratracheal administration could attenuate hyperoxia-induced lung, heart, and kidney injuries and the underlying regulatory mechanisms.
[World Journal of Stem Cells] |
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| MSCs may serve as a novel tool to investigate the full epigenome beyond DNA methylation, to explore other omics levels, and to perform functional assays.
[Trends in Endocrinology and Metabolism] |
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| STRM.BIO announced it has been awarded a Small Business Innovation Research (SBIR) grant for approximately $2,100,000 from the National Center for Advancing Translational Sciences at the National Institutes of Health.
[STRM.BIO (Cision US, Inc.)] |
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| November 7 – 8, 2022
London, England, United Kingdom |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | UT Health Science Center at San Antonio – San Antonio, Texas, United States |
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| | The Chinese University of Hong Kong – Hong Kong, China |
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| | Lehigh University – Bethlehem, Pennsylvania, Untied States |
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Cancer Stem Cell News
Cell Therapy News
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