Umbilical & Placental Cell News Volume 14.32 | Aug 18 2022

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    2022-08-18 | UPCN 14.32


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    Vol. 14.32 – 18 August, 2022
    TOP STORY

    Origination of LTR Retroelement-Derived NYNRIN Coincides with Therian Placental Emergence

    Researchers identified NYNRIN as another Ty3/Gypsy LTR retroelement-derived gene likely to contribute to placental emergence in the therian stem lineage.
    [Molecular Biology and Evolution]

    Abstract
    Stay up-to-date with the latest stem cell research by listening to the Stem Cell Podcast!
    PUBLICATIONSRanked by the impact factor of the journal

    Zika Virus Causes Placental Pyroptosis and Associated Adverse Fetal Outcomes by Activating GSDME

    Scientists demonstrated that Zika virus caused the pyroptosis of placental cells by activating the executor gasdermin E (GSDME) in vitro and in vivo.
    [eLife]

    Full Article

    Innate Immune Signaling in Trophoblast and Decidua Organoids Defines Differential Antiviral Defenses at the Maternal-Fetal Interface

    The authors developed matched trophoblast and decidua organoids from human placentas to define the relative contributions of these cells to antiviral defenses at the maternal-fetal interface.
    [eLife]

    Abstract

    Public Cord Blood Banks as a Source of Starting Material for Clinical Grade HLA-Homozygous Induced Pluripotent Stem Cells

    Scientists described their experience, from unit selection and donor reconsenting, in generating a CD34+ cell product as a starting material to produce HLA-homozygous induced pluripotent stem cell following a cost-effective and clinical grade-compliant procedure.
    [Stem Cell Research & Therapy]

    Full Article

    Repair Effect of Photobiomodulation Combined with Human Umbilical Cord Mesenchymal Stem Cells on Rats with Acute Lung Injury

    Photobiomodulation was emerged to intervene, in human umbilical cord MSCs through detecting cell proliferation, oxidative stress-related factors, and inflammatory factors.
    [Journal of Photochemistry and Photobiology B-Biology]

    Abstract

    Inflammasome Activation in Preeclampsia and Intrauterine Growth Restriction

    Investigators evaluated the inflammasome-dependent inflammation processes in placental tissue of women with preeclampsia and intrauterine growth restriction.
    [American Journal of Reproductive Immunology]

    Abstract
    Getting enough cord blood HSCs for transplantation isn't easy. But she's paving the way. Watch Suzan Imren's webinar.
    REVIEWS

    Clinical Progress and Preclinical Insights Into Umbilical Cord Blood Transplantation Improvement

    The authors review the current situations of umbilical cord blood manipulation in preclinical and clinical settings and discuss challenges and future directions.
    [Stem Cells Translational Medicine]

    Full ArticleGraphical Abstract
    INDUSTRY AND POLICY NEWS

    The UK Is Getting a New Prime Minister — What Will It Mean for Science?

    The race to decide who will become the new leader of the UK Conservative Party, and the country’s next Prime Minister, has less than a month left to run.
    [Nature]

    Press Release
    FEATURED EVENT

    Inborn Errors of Immunity: From Genetics to Basic Immunological Principles to Therapy

    December 5 – 7, 2022
    Virtual

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    JOB OPPORTUNITIES

    Assistant Member – Genes and Human Disease Research Program

    Oklahoma Medical Research Foundation – Oklahoma City, Oklahoma, United States

    Faculty Member – Faculty of Life and Health Sciences

    Shenzhen Institute of Advanced Technology – Shenzhen, China

    Postdoctoral Researcher – Regenerative Medicine

    National University of Ireland Galway – Galway, Ireland

    Research Officer – Devices for Synthetic Biology

    National Research Council Canada – Toronto, Ontario, Canada

    Senior Investigator – Cancer Research

    NIH National Cancer Institute – Bethesda, Maryland, United States

    > See All Jobs

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