Umbilical & Placental Cell News Volume 14.37 | Sep 22 2022

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    2022-09-22 | UPCN 14.37


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    Vol. 14.37 – 22 September, 2022
    TOP STORY

    Treatment with Amniotic Fluid Stem Cell Extracellular Vesicles Promotes Fetal Lung Branching and Cell Differentiation at Canalicular and Saccular Stages in Experimental Pulmonary Hypoplasia Secondary to Congenital Diaphragmatic Hernia

    Scientists tested whether amniotic fluid stem cells derived-extracellular vesicles exerted their regenerative effects at the canalicular and saccular stages, as these are translationally relevant for clinical intervention.
    [Stem Cells Translational Medicine]

    Graphical Abstract
    View tips on how to organize your lab bench space.
    PUBLICATIONSRanked by the impact factor of the journal

    Effects of Hypoxia-Preconditioned HucMSCs on Neovascularization and Follicle Survival in Frozen/Thawed Human Ovarian Cortex Transplanted to Immunodeficient Mice

    Investigators demonstrated that co-transplantation of hypoxia-preconditioned human umbilical cord MSC with ovarian tissue improved earlier vascularization of ovarian grafts in the early post-grafting period.
    [Stem Cell Research & Therapy]

    Full Article

    miR-515-5p Suppresses Trophoblast Cell Invasion and Proliferation through XIAP Regulation in Preeclampsia

    Scientists revealed that miR-515-5p was significantly upregulated in maternal serum from preeclampsia patients in comparison to normal pregnant women.
    [Molecular and Cellular Endocrinology]

    Full Article

    The Potential Role of Integrin Alpha 6 in Human Mesenchymal Stem Cells

    Researchers determined that the expression of integrin alpha 6 (ITGA6) and ITGA6 antisense RNA correlated with the proliferation, cell size, and differentiation potential.
    [Frontiers in Genetics]

    Full Article

    Wharton Jelly-Derived Mesenchymal Stem Cell Exosomes Induce Apoptosis and Suppress EMT Signaling in Cervical Cancer Cells as an Effective Drug Carrier System of Paclitaxel

    Human MSCs were isolated from Wharton’s jelly of umbilical cord tissue and cells were characterized by CD44, CD90, CD105, and CD34 staining.
    [PLoS One]

    Full Article

    Decellularized Wharton’s Jelly Scaffold Enhances Differentiation of Mesenchymal Stem Cells to Insulin-Secreting Cells

    A decellularized Wharton’s jelly scaffold was established and characterized by histological assessments, scanning electron microscopy, determination of residual DNA, and examination of the mechanical tensile property.
    [Tissue and Cell]

    AbstractGraphical Abstract
    Activate, expand, and differentiate your cells with cytokines, chemokines, and growth factors from STEMCELL Technologies.
    REVIEWS

    The Characteristics and Survival Potential under Sub-lethal Stress of Mesenchymal Stromal/Stem Cells Isolated from the Human Vascular Wall

    Investigators review the main findings regarding the MSCs isolated from the human vascular wall.
    [Stem Cells]

    AbstractGraphical Abstract

    Sex at the Interface: The Origin and Impact of Sex Differences in the Developing Human Placenta

    The authors discuss the findings from recent publications and consider the evidence for the genetic, hormonal, and immune mechanisms that are theorized to account for sex differences in early human placenta.
    [Biology of Sex Differences]

    Full Article
    INDUSTRY AND POLICY NEWS

    CellResearch Corporation (CRC) Announces Positive Results of Phase I Study For CorLiCyte®

    CellResearch Corporation announced it has successfully closed the first Phase I study in CorLiCyte®, a stem cell therapy derived from umbilical cord lining stem cells, with research partners at the University of Colorado, Anschutz Medical Campus and ClinImmune Cell and Gene Therapy.
    [CellResearch Corporation (PR Newswire)]

    Press Release

    MIMEDX Announces Launch Of AXIOFILL™

    MiMedx Group, Inc. announced the launch of AXIOFILL™, an ECM Particulate product derived from human placental tissue. AXIOFILL is the first and only human placental-derived particulate product available for Surgical Recovery procedures.
    [MiMedx Group, Inc.]

    Press Release
    FEATURED EVENT

    Cell Symposia: Multifaceted Mitochondria

    November 6 – 8, 2022
    Seville, Spain

    > See All Events

    JOB OPPORTUNITIES

    Assistant Professor – Stem Cell Biology

    University of California Santa Cruz – Santa Cruz, California, United States

    Research Specialist – Stem Cell Biology

    Karolinska Institutet – Flemingsberg, Sweden

    Assistant/Associate Professor – Clinical Pathology

    USC Children’s Hospital Los Angeles – Los Angeles, California, United States

    Research Technologist – Center for Regenerative Medicine

    Harvard Stem Cell Institute – Boston, Massachusetts, United States

    Research Technologist – Tissue and Cell Biology

    STEMCELL Technologies, Inc. – Vancouver, British Columbia, Canada

    > See All Jobs

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