Umbilical & Placental Cell News Volume 14.41 | Oct 20 2022

October 20, 2022

115

2022-10-20 | UPCN 14.41

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Vol. 14.41 – 20 October, 2022

TOP STORY

Secretome of Human Umbilical Cord Mesenchymal Stem Cell Maintains Skin Homeostasis by Regulating Multiple Skin Physiological Function

Researchers evaluated the therapeutic potential of the secretome of human umbilical cord MSCs for dermatological diseases in adult human skin cells, ex vivo skin tissue, and a 3D skin model.
[Cell and Tissue Research]

Abstract

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PUBLICATIONSRanked by the impact factor of the journal

Naïve Pluripotent-Like Characteristics of Non-Tumorigenic Muse Cells Isolated from Human Amniotic Membrane

SSEA-3(+) cells from human amniotic membrane MSCs were compared with human bone marrow-multilineage-differentiating stress-enduring (Muse) cells, in order to investigate similarities and differences of key charachteristics between the two cell types.
[Scientific Reports]

Full Article

Therapeutic Effect of Human Umbilical Cord Mesenchymal Stem Cells in Early Traumatic Osteonecrosis of the Femoral Head

The authors explored the available evidence for the therapeutic effect of human umbilical cord MSCs on early-stage traumatic osteonecrosis of the femoral head.
[Journal of Orthopaedic Translation]

Full Article

Galangin Induces the Osteogenic Differentiation of Human Amniotic Mesenchymal Stem Cells via the JAK2/STAT3 Signaling Pathway

Scientists explored the potential pro-osteogenic differentiation effect of galangin, a flavonoid derived from Alpinia officinarum, on human amniotic MSCs and the underlying molecular mechanism.
[European Journal of Pharmacology]

Abstract Graphical Abstract

Gelatin Microspheres Loaded with Wharton’s Jelly Mesenchymal Stem Cells Promote Acute Full-Thickness Skin Wound Healing and Regeneration in Mice

3D gelatin microspheres (GM) had strong biocompatibility, and in comparison with two-dimensional adherent culturing, GM loading increased the cell viability, and proliferation ability of Wharton’s jelly MSCs.
[Advances in Wound Care]

Abstract

Differentiation of Human Wharton Jelly Mesenchymal Stem Cells into Germ-Like Cells; Emphasis on Evaluation of Germ-Long Non-coding RNAs

Investigators developed a modified differentiation process and identified a panel of GermlncRNAs related to germ-like cells.
[Molecular Biology Reports]

Abstract

Kevin Shoulars found a faster, more reproducible way to assess the potency of core blood units for transplant. Watch the webinar.

REVIEWS

Amniotic Stem Cells as a Source of Regenerative Medicine to Treat Female Infertility

The authors summarize the current standing and progress of human amniotic epithelial stem cells, amniotic MSCs, and amniotic fluid stem cells in the field of reproductive medicine.
[Human Cell]

Full Article

Ex Vivo Perfusion of the Human Placenta to Investigate Pregnancy Pathologies

Investigators review the key studies which have utilized the ex vivo placenta perfusion model to study different aspects of such pregnancy pathologies.
[Placenta]

Full Article

INDUSTRY AND POLICY NEWS

Smart Immune and Greater Paris University Hospitals (AP-HP) Begin Groundbreaking Phase I/II Trial with ProTcell™, a Thymus-Empowered T Cell Therapy Platform, in Adults with Blood Cancers

Smart Immune SAS announced that SMART102, a human T-lymphoid progenitor cell injection derived from cord blood using SmartImmune’s ProTcell™ platform, has entered clinical testing in a trial sponsored and led by Great Paris University Hospitals.
[Smart Immune SAS]

Press Release

FEATURED EVENT

Umbilical & Placental Cell News Volume 14.41 | Oct 20 2022

Secretome of Human Umbilical Cord Mesenchymal Stem Cell Maintains Skin Homeostasis by Regulating Multiple Skin Physiological Function

Naïve Pluripotent-Like Characteristics of Non-Tumorigenic Muse Cells Isolated from Human Amniotic Membrane

Therapeutic Effect of Human Umbilical Cord Mesenchymal Stem Cells in Early Traumatic Osteonecrosis of the Femoral Head

Galangin Induces the Osteogenic Differentiation of Human Amniotic Mesenchymal Stem Cells via the JAK2/STAT3 Signaling Pathway

Gelatin Microspheres Loaded with Wharton’s Jelly Mesenchymal Stem Cells Promote Acute Full-Thickness Skin Wound Healing and Regeneration in Mice

Differentiation of Human Wharton Jelly Mesenchymal Stem Cells into Germ-Like Cells; Emphasis on Evaluation of Germ-Long Non-coding RNAs

Amniotic Stem Cells as a Source of Regenerative Medicine to Treat Female Infertility

Ex Vivo Perfusion of the Human Placenta to Investigate Pregnancy Pathologies

Smart Immune and Greater Paris University Hospitals (AP-HP) Begin Groundbreaking Phase I/II Trial with ProTcell™, a Thymus-Empowered T Cell Therapy Platform, in Adults with Blood Cancers

Emerging Cellular Therapies at the Forefront of Cancer Immunotherapy

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Postdoctoral Position – Computational Biology

Postdoctoral Fellow and Research Associate – Obstetrics and Gynecology

Manager – Laboratory Services

Postdoctoral Scholar – Stem Cell-Based Therapy

Assistant/Associate Faculty Position – Cancer Research

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