 | | Vol. 14.44 – 10 November, 2022 |
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| The authors associated decellularized human amniotic membrane with adipose-derived MSCs, as a therapy strategy for second-degree burns in a preclinical model.
[Biofabrication] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators showed that histocompatibility and CD14+ monocyte cells had an impact on human placenta-derived decidua stromal cells immunomodulation but frozen–thawed or freshly prepared cells did not.
[Cytotherapy] |
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| Researchers presented in vitro models of human trophoblast differentiation, describing both primary and human pluripotent stem cells-derived trophoblast stem cell as a tool to study early placental development and disease in multiple settings.
[Placenta] |
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| Scientists isolated and identified a placental MSC line carrying compound heterozygote variations in hTERT that lost telomerase activity, showed a typical surface phenotype of MSCs, and was able to differentiate into multiple cell lineages.
[Biochemical and Biophysical Research Communications] |
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| The authors tested if eliminating p38 would reduce oxidative stress induced cell fates like cellular senescence, epithelial-mesenchymal transition, and inflammation induced by these processes in chorion trophoblast cells.
[American Journal of Reproductive Immunology] |
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| Researchers showed that chemical inhibition of mitochondrial fission in cultured placental trophoblast cells led to an increase in mitochondrial fusion and improved the physiological state of these cells.
[Molecular Biology Reports] |
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| The authors highlight various ancient and new applications of amnion in research and clinical applications, from regenerative medicine to cancer therapy, focusing on articles published during the last decade.
[Journal of Biomaterials Applications] |
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| The FDA has committed to exploring alternative methods to replace laboratory animals in developing new drugs and products.
[Nature News] |
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| December 12 – 13, 2022
Ghent, Belgium |
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| | Babraham Institute – Babraham, England, United Kingdom |
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| | UC San Francisco – San Francisco, California, United States |
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| | NUI Galway – Galway, Ireland |
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| | University of British Columbia – Vancouver, British Columbia, Canada |
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| | University of Cambridge – Cambridge, England, United Kingdom |
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