Umbilical & Placental Cell News Volume 14.45 | Nov 17 2022

November 17, 2022

2022-11-16 | UPCN 14.45

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Vol. 14.45 – 17 November, 2022

TOP STORY

Dissecting Heterogeneity Reveals a Unique BAMBI^highMFGE8^high Subpopulation of Human UC-MSCs

Investigators drew a large-scale single-cell transcriptomic atlas and identified three clusters, representing the primed, intermediate, and stem statuses within human umbilical cord-derived-MSCs individually.
[Advanced Science]

Full Article

Five tips for returning to the lab after time off

PUBLICATIONSRanked by the impact factor of the journal

Comparison and Investigation of Exosomes from Human Amniotic Fluid Stem Cells and Human Breast Milk in Alleviating Neonatal Necrotizing Enterocolitis

The authors compared the intervention effects of two types of exosomes on neonatal necrotizing enterocolitis mouse model and revealed their respective regulatory mechanisms.
[Stem Cell Reviews and Reports]

Full Article Graphical Abstract

Human Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Protect against MCD-Induced NASH in a Mouse Model

Researchers investigated the efficiency of human umbilical cord-MSC-derived exosomes in protecting against nonalcoholic steatohepatitis using an methionine–choline-deficient (MCD)-induced mouse model.
[Stem Cell Research & Therapy]

Full Article

Osteogenic Differentiation and Proliferation Potentials of Human Bone Marrow and Umbilical Cord-Derived Mesenchymal Stem Cells on the 3D-Printed Hydroxyapatite Scaffolds

Investigators evaluated the proliferation and osteogenic differentiation potentials of MSCs cultured on 2 types of 3D-printed hydroxyapatite (HA), including a 3D-printed HA and biomimetic calcium phosphate-coated 3D-printed HA.
[Scientific Reports]

Full Article

Multiplexed Analysis of Gene Expression and Chromatin Accessibility of Human Umbilical Cord Blood Using scRNA-Seq and scATAC-Seq

Scientists identified several distinct cell types, erythroid cell, T cell, B cell, erythroid precursor cells, NK cell, and endothelial progenitor cell, and subpopulations in umbilical cord blood cells.
[Molecular Immunology]

Abstract

MRI Tracking of Human Wharton’s Jelly Stem Cells Seeded onto Acellular Dermal Matrix Labeled with Superparamagnetic Iron Oxide Nanoparticles in Burn Wounds

Researchers investigated tracking of human Wharton’s jelly stem cells seeded onto an acellular dermal matrix and labeled with superparamagnetic iron oxide nanoparticles by magnetic resonance imaging in burn injury.
[Burns & Trauma]

Full Article

REVIEWS

Here and There a Trophoblast, a Transcriptional Evaluation of Trophoblast Cell Models

The authors integrate and assess transcriptomic data of cell-based models of human trophoblast and stem cells alongside in vivo samples to identify the utility and applicability of these models.
[Cellular and Molecular Life Sciences]

Abstract

INDUSTRY AND POLICY NEWS

Amniotics Led Consortium Selected for EIC-Pathfinder Grant of €3.8 Million from the European Innovation Council

Amniotics AB announced it has been invited to finalise a grant agreement with the European Innovation Council (EIC) as part of a consortium set to receive a grant of €3,8 Million from the EIC Pathfinder program.
[Amniotics AB]

Press Release

FEATURED EVENT

Umbilical & Placental Cell News Volume 14.45 | Nov 17 2022

Dissecting Heterogeneity Reveals a Unique BAMBI^highMFGE8^high Subpopulation of Human UC-MSCs

Comparison and Investigation of Exosomes from Human Amniotic Fluid Stem Cells and Human Breast Milk in Alleviating Neonatal Necrotizing Enterocolitis

Human Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Protect against MCD-Induced NASH in a Mouse Model

Osteogenic Differentiation and Proliferation Potentials of Human Bone Marrow and Umbilical Cord-Derived Mesenchymal Stem Cells on the 3D-Printed Hydroxyapatite Scaffolds

Multiplexed Analysis of Gene Expression and Chromatin Accessibility of Human Umbilical Cord Blood Using scRNA-Seq and scATAC-Seq

MRI Tracking of Human Wharton’s Jelly Stem Cells Seeded onto Acellular Dermal Matrix Labeled with Superparamagnetic Iron Oxide Nanoparticles in Burn Wounds

Here and There a Trophoblast, a Transcriptional Evaluation of Trophoblast Cell Models

Amniotics Led Consortium Selected for EIC-Pathfinder Grant of €3.8 Million from the European Innovation Council

4^th Growth Factors in Regeneration and Regenerative Medicine Conference

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Postdoctoral Fellow – Mammalian Morphogenesis

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