Umbilical & Placental Cell News Volume 14.46 | Nov 24 2022

    By
    Bob
    -
    0
    95








    2022-11-24 | UPCN 14.46


    Umbilical-and-Placental-Cell-News-email-header (1)
    Vol. 14.46 – 24 November, 2022
    TOP STORY

    Bioscaffold Developed With Decellularized Human Amniotic Membrane Seeded With Mesenchymal Stromal Cells: Assessment of Efficacy and Safety Profiles in a Second-Degree Burn Preclinical Model

    Researchers associated decellularized human amniotic membrane with adipose-derived MSCs, as a therapy strategy for second-degree burns in a preclinical model.
    [Biofabrication]

    Abstract
    Getting enough cord blood HSCs for transplantation isn't easy. But she's paving the way. Watch Suzan Imren's webinar.
    PUBLICATIONSRanked by the impact factor of the journal

    NETs Promote ROS Production To Induce Human Amniotic Epithelial Cell Apoptosis via ERK1/2 Signaling in Spontaneous Preterm Birth

    Investigators found that neutrophil extracellular traps (NETs) could promote the apoptosis of human amniotic epithelial cells via ERK1/2 pathways dependent on reactive oxygen species (ROS) release.
    [Journal of Reproductive Immunology]

    Abstract

    Quantitative Proteomic Analysis of Exosomes From Umbilical Cord Mesenchymal Stem Cells and Rat Bone Marrow Stem Cells

    Scientists used the parallel accumulation serial fragmentation combined with the data-independent acquisition method to quantify exosomes derived from human umbilical cord MSCs and rat bone marrow stem cells.
    [Proteomics]

    Abstract

    B2 Cells Contribute to the Pathophysiology of Hypertension in Response to Placental Ischemia

    Researchers evaluated whether an adoptive transfer of B2 cells from reduced uterine perfusion pressure rats would cause hypertension, natural killer cell activation, and complement activation during pregnancy through production of the angiotensin II type 1 receptor.
    [American Journal of Physiology-Renal Physiology]

    Abstract

    Effects of Green Light-Emitting Diode Irradiation on Neural Differentiation of Human Umbilical Cord Matrix-Derived Mesenchymal Cells; Involvement of MAPK Pathway

    Scientists investigated the effects of green LED irradiation, retinoic acid, and their combination on the differentiation of human umbilical cord matrix-derived mesenchymal cells into neural lineage as well as the mechanisms involved.
    [Biochemical and Biophysical Research Communications]

    Abstract

    Placenta-Derived Extracellular Vesicles from Preeclamptic and Healthy Pregnancies Impair Ex Vivo Vascular Endothelial Function

    Syncytiotrophoblast-derived extracellular vesicles (STBEVs) were collected by perfusion of placentas from women with normal pregnancies (NP) or preeclampsia (PE). Mesenteric arteries from pregnant rats were incubated overnight with NP or PE STBEVs, and vascular function was assessed by wire myography.
    [Bioscience Reports]

    Abstract
    Image of man completing the on-demand CFU assay course on his laptop.
    REVIEWS

    Experimental Human Placental Models for Studying Uptake, Transport, and Toxicity of Micro- and Nanoplastics

    Scientists recapitulate different human placental models, summarize the current understanding of placental uptake, transport, and toxicity of micro- and nanoplastics and define knowledge gaps.
    [Science of the Total Environment]

    AbstractGraphical Abstract
    INDUSTRY AND POLICY NEWS

    UC San Diego Sanford Stem Cell Institute Launches Stem Cells into Space

    The University of California (UC) San Diego Sanford Stem Cell Institute will lead its first launch of hematopoietic stem cells into space.
    [UC San Diego]

    Press Release
    FEATURED EVENT

    AACR Special Conference: Acute Myeloid Leukemia and Myelodysplastic Syndrome

    January 23 – 25, 2023
    Austin, Texas, United States

    > See All Events

    JOB OPPORTUNITIES

    Lead Associate – Clinical Trials

    Takeda – Boston, Massachusetts, United States

    Postdoctoral Fellow – Cancer/Stem Cell Biology

    City of Hope – Los Angeles, California, United States

    Postdoctoral Research Associate – Human Umbilical Cord Blood

    University of Edinburgh – Edinburgh, Scotland, United Kingdom

    PhD positions – EuReCa PhD Program

    Institut Curie – Paris, France

    Senior Program Associate – Science in the City

    STEMCELL Technologies, Inc. – Boston, Massachusetts, United States

    > See All Jobs

    Submit an article, publication, job or event
    Brought to you by
    stemcell-logo-for newsletter-2
    Cord Blood News Twitter