| Vol. 14.47 – 1 December, 2022 |
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| Researchers described a protocol for the preparation of high-quality single-cell suspensions from human placental tissues—namely, the basal plate, placental villi, and chorioamniotic membranes. [Nature Protocols] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Human trophoblast stem cells were used to corroborate the role of glial cells missing-1 (GCM1) in syncytiotrophoblast formation and uncover its critical role in extravillous trophoblast development. [Proceedings of the National Academy of Sciences of the United States of America] |
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| Scientists tested whether small extracellular vesicles derived from Nrf2-overexpressing human amniotic mesenchymal stem cells could protect against acute lung injury. [Biology Direct] |
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| The authors investigated the role of miR-141–3p in autophagy induced by hypoxia in human placental trophoblast cells. They found that hypoxia induced autophagy in trophoblast cells and dramatically elevated the expression of miR-141–3p. [Reproductive Biology] |
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| Scientists demonstrated the relationship between glucose and the activation of the NLR family of pyrin domain-containing 3 inflammasome. [Cell and Tissue Banking] |
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| Researchers compared the effectiveness of amniotic membrane and amniotic membrane pretreated with monophosphoryl lipid A (MPLA) for repairing the fascia of the abdomen with tension sutures. [Cell and Tissue Banking] |
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| Investigators studied regulation of the expression of placental growth factor that play an important role in the trophoblast cells functions and reduced production of which by the placenta is associated with gestational complications. [Bulletin of Experimental Biology and Medicine] |
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| The authors review the biological and molecular properties that define authentic human trophoblast stem cells (hTSCs), the trophoblast potential of distinct pluripotent states, and methods for inducing hTSCs in somatic cells by direct reprogramming. [Cellular and Molecular Life Sciences] |
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| Scientists indicate that transplanting umbilical cord blood following ex vivo expansion can accelerate initial engraftment. [Transplantation and Cellular Therapy] |
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| Americord Registry® has partnered with Veritas Genetics to develop and offer newborn and maternal whole-genome screening to Americord families. [Americord Registry® (Newsmatics, Inc.)] |
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| February 5 – 8, 2023 Keystone, Colorado, United States |
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| Takeda – Boston, Massachusetts, United States |
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| RWTH Aachen University – Aachen, Germany |
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| City of Hope – Los Angeles, California, United States |
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| University of Edinburgh – Edinburgh, Scotland, United Kingdom |
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| University of Pennsylvania – Philadelphia, Pennsylvania, United States |
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