 | | Vol. 15.07 – 2 March, 2023 |
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| Investigators selected three mutant mouse lines, Atp11a, Smg9, and Ssr2, that presented with placental and heart defects in a recent phenotyping screen, resulting in embryonic lethality.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The authors investigated the therapeutic efficacy and the possible mechanism of combined curcumin and human umbilical cord-derived-MSC treatment in acute ischemic stroke.
[Journal of Neuroinflammation] |
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| A modified chemical resetting protocol allowed for the fast and efficient conversion of conventional pluripotent stem cells (PSCs) into trophoblast stem cells (TSCs), entailing shutdown of pluripotency genes and full activation of the trophoblast master regulators, without induction of amnion markers.
[EMBO Reports] |
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| Scientists reported that benzene exposure during pregnancy led to maternal immune activation associated with increased fetal resorptions, fetal growth, and abnormal placenta development. They demonstrated the existence of a sexual dimorphic response to benzene exposure in male and female placentas.
[iScience] |
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| Researchers demonstrated that deletion of an enhancer that confered GATA2 expression in fetal progenitors elevated Toll-Like Receptor (TLR) TLR1/2 and TLR2/6 expression and signaling.
[iScience] |
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| Scientists utilized an aptamer-based platform to characterize 1,310 amniotic fluid proteins and found that the proteome undergoes substantial changes with term labor.
[Scientific Reports] |
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| The authors describe the hematologic differences among neonatal subgroups and the major underlying pathogenic mechanisms. Issues that should be taken into account when interpreting neonatal hematological parameters are also highlighted.
[Annals of Hematology] |
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| Researchers in the United Kingdom (UK) breathed a cautious sigh of relief yesterday after the government struck a deal with the European Union (EU) to fix post-Brexit disputes over issues including trade across Northern Ireland’s border.
[ScienceInsider] |
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| April 23 – 28, 2023
Cancun, Mexico |
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| | The University of Melbourne – Melbourne, Australia |
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| | Medical College of Wisconsin – Milwaukee, Wisconsin, United States |
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| | Beth Israel Deaconess Medical Center – Boston, Massachusetts, United States |
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| | Georg-Speyer-Haus – Frankfurt, Germany |
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| | St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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