 | | Vol. 15.10 – 23 March, 2023 |
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| To decipher cell compositions and developmental processes, the authors systematically profiled the single-cell transcriptomes of trophoblast cells from extraembryonic tissues and placentae at one-day intervals.
[Cell Discovery] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers explored the effect of human umbilical cord MSCs-conditioned medium on granulosa tumor cell line cells at low or high density.
[Stem Cell Research & Therapy] |
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| Placenta powder, made from decellularized human placenta, was physically incorporated into synthetic poly(ethylene glycol)-based hydrogels via ultraviolet-initiated thiol-ene coupling.
[Biomacromolecules] |
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| Injection of human placental MSCs improved ovarian function and reproductive ability of premature ovarian insufficiency rats compared to the sham and hormone groups.
[Journal of Ovarian Research] |
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| Scientists explored the role of rapamycin combined with human umbilical cord-derived MSCs in osteoarthritis (OA) rabbits in vivo. OA rabbits received an intra-articular injection of a collagenase solution.
[Immunopharmacology And Immunotoxicology] |
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| Investigators revealed the efficacy of human umbilical cord MSCs in alleviating acute graft-versus-host disease in a murine model, with striking changes in metabolism and significantly elevated phytosphingosine levels due to sphingolipid metabolism.
[Experimental Hematology] |
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| Vascular dementia (VaD) rat model was established by bilateral common carotid artery ligation and human umbilical cord MSC-derived extracellular vesicles (EVs) were extracted. VaD rats were injected with Evs through the tail vein.
[Synapse] |
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| Scientists summarize the latest progress in trophoblastic ferroptosis research on placental-related diseases, provide references for further understanding of its pathogenesis, and propose new strategies for the prevention and treatment of placental-related diseases.
[Reproductive Sciences] |
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| Researchers from the University of Sydney have been awarded $47 million to support 32 research projects, including investigations of younger-onset dementia, the treatment of blinding eye diseases through stem cell therapy, and the impact of e-cigarette use by adolescents.
[The University of Sydney] |
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| July 24 – 28, 2023
Boston, Massachusetts, United States |
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| | Lund University – Lund, Sweden |
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| | Columbia University – New York, New York, United States |
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| | Karolinska Institute – Solna, Sweden |
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| | Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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| | Yale School of Medicine – New Haven, Connecticut, United States |
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