Umbilical & Placental Cell News Volume 15.11 | Mar 30 2023

March 30, 2023

100

2023-03-30 | UPCN 15.11

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Vol. 15.11 – 30 March, 2023

TOP STORY

Preferential Hematopoietic Differentiation in Induced Pluripotent Stem Cells Derived from Human Umbilical Cord Arterial Endothelial Cells

Researchers revealed that human umbilical arterial endothelial cell–derived induced pluripotent stem cells (iPSCs) exhibited indistinguishable pluripotency in comparison with human embryonic stem cells and human iPSCs derived from other tissues of origin.
[Arteriosclerosis Thrombosis And Vascular Biology]

Abstract

Find out the estimated cell frequencies and percentages of more than 35 cell types in normal human blood-related sources.

PUBLICATIONSRanked by the impact factor of the journal

MicroRNAs of Extracellular Vesicles Derived from Mesenchymal Stromal Cells Alleviate Inflammation in Dry Eye Disease by Targeting the IRAK1/TAB2/NF-κB Pathway

Scientists investigated the efficacy and mechanisms of human umbilical cord-derived MSC-derived extracellular vesicles in a mouse model of desiccation-induced dry eye disease.
[Ocular Surface]

Full Article

In Vitro Evaluation of Genipin-Crosslinked Gelatin Hydrogels for Vocal Fold Injection

Some selected formulations proceeded with rheology, pore size, chemical analysis, and in vitro cellular activity of Wharton’s Jelly MSCs, to determine the safety application of the selected hydrogels, for future cell delivery prospects.
[Scientific Reports]

Full Article

Schisandrin B Improves the Hypothermic Preservation of Celsior Solution in Human Umbilical Cord Mesenchymal Stem Cells

The authors investigated the protective effects of Schisandrin B on the hypothermic preservation of human umbilical cord MSCs isolated from Wharton’s jelly.
[Tissue Engineering and Regenerative Medicine]

Abstract

Protective Effects of Human Amniotic Membrane Derived Mesenchymal Stem Cells (hAMSCs) Secreted Factors on Mouse Spermatogenesis and Sperm Chromatin Condensation Following Unilateral Testicular Torsion

Investigators evaluated the protective effects of hAMSCs secreted factors on mouse sperm chromatin condensation and spermatogenesis improvement after ischemia/reperfusion injury.
[Annals Of Anatomy-Anatomischer Anzeiger]

Abstract

Hypoxia-Treated Umbilical Mesenchymal Stem Cell Alleviates Spinal Cord Ischemia-Reperfusion Injury in SCI by Circular RNA circOXNAD1/ miR-29a-3p/ FOXO3a Axis

Researchers studied the therapeutic potential of hypoxia-induced exosomal circular RNA OXNAD1 from human umbilical cord MSCs against spinal cord ischemia-reperfusion.
[Biochemistry And Biophysics Reports]

Full Article

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REVIEWS

Impact of the Source of Hematopoietic Stem Cells on Immune Reconstitution after Transplantation: A Systematic Review

Scientists analyze the kinetic of immune reconstitution among umbilical cord blood, peripheral blood, and bone marrow in hematopoietic stem cell transplant patients by focusing on natural killer cells, B and T lymphocytes, and neutrophils.
[European Journal Of Haematology]

Abstract

INDUSTRY AND POLICY NEWS

FDA Floats Oncology Authorization Shake-Up, Pitching ‘One-Trial’ Model for Accelerated and Full Approval

The FDA outlined plans to move away from single-arm studies and instead favor randomized controlled trials that can potentially serve as the basis for both accelerated and full approval.
[Fierce Biotech]

Press Release

FEATURED EVENT

Umbilical & Placental Cell News Volume 15.11 | Mar 30 2023

Preferential Hematopoietic Differentiation in Induced Pluripotent Stem Cells Derived from Human Umbilical Cord Arterial Endothelial Cells

MicroRNAs of Extracellular Vesicles Derived from Mesenchymal Stromal Cells Alleviate Inflammation in Dry Eye Disease by Targeting the IRAK1/TAB2/NF-κB Pathway

In Vitro Evaluation of Genipin-Crosslinked Gelatin Hydrogels for Vocal Fold Injection

Schisandrin B Improves the Hypothermic Preservation of Celsior Solution in Human Umbilical Cord Mesenchymal Stem Cells

Protective Effects of Human Amniotic Membrane Derived Mesenchymal Stem Cells (hAMSCs) Secreted Factors on Mouse Spermatogenesis and Sperm Chromatin Condensation Following Unilateral Testicular Torsion

Hypoxia-Treated Umbilical Mesenchymal Stem Cell Alleviates Spinal Cord Ischemia-Reperfusion Injury in SCI by Circular RNA circOXNAD1/ miR-29a-3p/ FOXO3a Axis

Impact of the Source of Hematopoietic Stem Cells on Immune Reconstitution after Transplantation: A Systematic Review

FDA Floats Oncology Authorization Shake-Up, Pitching ‘One-Trial’ Model for Accelerated and Full Approval

World Oncology Cell Therapy Congress

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