Umbilical & Placental Cell News Volume 15.13 | Apr 13 2023

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    2023-04-13 | UPCN 15.13


    Umbilical-and-Placental-Cell-News-email-header (1)
    Vol. 15.13 – 13 April, 2023
    TOP STORY

    Metabolomic Analysis of Maternal Mid-Gestation Plasma and Cord Blood in Autism Spectrum Disorders

    Scientists characterized metabolomic profiles in autism spectrum disorder using plasma samples collected in the Norwegian Autism Birth Cohort from mothers at weeks 17–21 gestation.
    [Molecular Psychiatry]

    AbstractPress Release
    Kevin Shoulars found a faster, more reproducible way to assess the potency of core blood units for transplant. Watch the webinar.
    PUBLICATIONSRanked by the impact factor of the journal

    Activation of Atg5-Dependent Placental Lipophagy Ameliorates Cadmium-Induced Fetal Growth Restriction

    Researchers explored the role of placental lipophagy in cadmium-induced fetal growth restriction utilizing case-control study, animal experiments, and cultures of primary human placental trophoblast cells.
    [Environmental Pollution]

    AbstractGraphical Abstract

    High Dimensional Analysis Reveals Distinct NK Cell Subsets but Conserved Response to Stimulation in Umbilical Cord Blood and Adult Peripheral Blood

    Investigators showed that umbilical cord blood natural killer cells expressed slightly higher levels of the immune checkpoints PD-1, TIGIT, and CD96 compared to their adult peripheral blood counterparts.
    [European Journal of Immunology]

    Abstract

    Lin28 Promoting the Protective Effect of PMSCs on Hepatic Ischaemia–Reperfusion Injury by Regulating Glucose Metabolism

    Scientists examined the role of the Lin28 protein in the regulation of glucose metabolism in human placental MSCs (PMSCs).
    [Journal Of Cellular And Molecular Medicine]

    Full Article

    Application of HUC-MSCs in Rat SCI Model

    Human umbilical cord (HUC) MSCs transplantation could partially recover the motor ability of rats with spinal cord injury (SCI) by promoting nerve cell regeneration.
    [Asaio Journal]

    Abstract

    High TXNIP Expression Accelerates the Migration and Invasion of the GDM Placenta Trophoblast

    The expression and localization of thioredoxin-interacting protein (TXNIP) in the placenta of gestational diabetes mellitus (GDM) patients and the health control was investigated.
    [BMC Pregnancy and Childbirth]

    Full Article

    Combined Application of Human Amniotic Membrane Mesenchymal Stem Cells and a Modified PGS-Co-PCL Film in an Experimental Model of Myocardial Ischemia–Reperfusion Injury

    Human amniotic membrane MSCs positively affected the repair of myocardial ischemia–reperfusion injury by stimulating endogenous repair mechanisms.
    [Applied Biochemistry and Biotechnology]

    Abstract
    Submit your best cell image to the #StemCellfie contest!
    REVIEWS

    Functions and Regulatory Mechanisms of Resting Hematopoietic Stem Cells: A Promising Targeted Therapeutic Strategy

    The authors describe the functions of HSCs, analyze the regulatory mechanisms that affect their resting state, and discuss the relationship between resting HSCs and different diseases, with a view to providing guidance for the future clinical implementation of related targeted treatments.
    [Stem Cell Research & Therapy]

    Full Article
    INDUSTRY AND POLICY NEWS

    Bailey Recieves Philanthropic Research Grant

    Pitt Pediatrics congratulates Dr. Kelly M. Bailey for her recent awardance of a research grant from the Charlie Landers Foundation through the Children’s Hospital Foundation of Pittsburgh.
    [University of Pittsburgh]

    Press Release
    FEATURED EVENT

    11th International Meeting of the Stem Cell Network 2023

    May 16 – 17, 2023
    Aachen, Germany

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    JOB OPPORTUNITIES

    Specialist – Cell Processing

    Dana-Farber Cancer Institute – Boston, Massachusetts, United States

    PhD Position – Biology and Nutrition

    Université de Lausanne – Lausanne, Switzerland

    Research Faculty Position – Placental Biology and Gynecologic Oncology

    Medical College of Wisconsin – Milwaukee, Wisconsin, United States

    Research Fellow – Neuromuscular Disease

    Mayo Clinic – Rochester, Minnesota, United States

    Director – Cardiovascular Tissue Engineering

    Medical College of Wisconsin – Milwaukee, Wisconsin, United States

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