Umbilical & Placental Cell News Volume 15.17 | May 11 2023

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    2023-05-11 | UPCN 15.17


    Umbilical-and-Placental-Cell-News-email-header (1)
    Vol. 15.17 – 11 May, 2023
    TOP STORY

    Biomimetic Scaffold-Based Stem Cell Transplantation Promotes Lung Regeneration

    Investigators constructed an artificial three-dimensional biomimetic scaffold-based MSCs implant to establish a beneficial regeneration niche for endogenous stem cells in situ lung regeneration.
    [Bioengineering & Translational Medicine]

    Full Article
    Image of erythroblasts which were simply & efficiently generated from PSCs using the STEMdiff Erythroid Kit.
    PUBLICATIONSRanked by the impact factor of the journal

    The Impacts of Total Body Irradiation on Umbilical Cord Blood Hematopoietic Stem Cell Transplantation

    Researchers conducted a retrospective analysis of the outcomes of 136 patients receiving umbilical cord blood transplantation (UCBT) and evaluated the impacts of total body irradiation on UCBT outcomes.
    [Therapeutic Advances in Hematology]

    Full Article

    Human Placental Mesenchymal Stem Cell-Derived Exosomes in Combination with Hyperbaric Oxygen Synergistically Promote Recovery after Spinal Cord Injury in Rats

    Scientists investigated the combined effects of human placenta MSCs-derived exosomes along with hyperbaric oxygen in the recovery of spinal cord injury in rats.
    [Neurotoxicity Research]

    Abstract

    Trichloroethylene Metabolite S-(1,2-Dichlorovinyl)-L-cysteine Stimulates Changes in Energy Metabolites and Amino Acids in the BeWo Human Placental Trophoblast Model during Syncytialization

    Researchers investigated S-(1,2-dichlorovinyl)-l-cysteine-induced changes to energy metabolism and amino acids during forskolin-stimulated syncytialization in BeWo cells, a human villous trophoblastic cell line that modeled syncytialization in vitro.
    [Chemical Research In Toxicology]

    AbstractGraphical Abstract

    Characterization of Xenobiotic and Steroid Disposition Potential of Human Placental Tissue and Cell Lines (BeWo, JEG-3, JAR, and HTR-8/SVneo) by Quantitative Proteomics

    Investigators characterized the abundance of proteins involved in xenobiotic and steroid disposition in human placental tissue and compared the tissue proteomics data with four placental cell lines.
    [Drug Metabolism and Disposition]

    Abstract

    Human Umbilical Cord Blood Mononuclear Cells Ameliorate Ischemic Brain Injury via Promoting Microglia/Macrophages M2 Polarization in MCAO Rats

    The authors explored whether human umbilical cord blood mononuclear cells treatment for cerebral infarction via regulation of microglia/macrophage polarization.
    [Experimental Brain Research]

    Abstract
    Guide to everything you need to know about cell separation.
    REVIEWS

    Potential Applications of Mesenchymal Stem Cells and Their Derived Exosomes in Regenerative Medicine

    Investigators discuss the distinct advantages of both MSCs and their secreted exosomes, including their immunomodulatory effects, lack of immunogenicity, and recruitment to damaged areas.
    [Expert Opinion On Biological Therapy]

    Full ArticleGraphical Abstract
    INDUSTRY AND POLICY NEWS

    Maryland Stem Cell Research Commission Announces Over $14 Million in Awards to Accelerate Cures

    The Maryland Stem Cell Research Fund Commission has announced over $14.1 million in grant awards to promote innovative research that will strengthen and advance stem cell treatments and technologies in Maryland.
    [TEDCO]

    Press Release
    FEATURED EVENT

    The Aging Genome: From Mechanisms to Disease

    June 4 – 7, 2023
    Heidelberg, Germany

    > See All Events

    JOB OPPORTUNITIES

    Production Manager – Equine MSCs

    Boehringer Ingelheim – Ingelheim, Germany

    Senior Associate – Cell and Organoid Biorepository

    Roche Institute of Translational Bioengineering – Zurich, Switzerland

    Research Associate – Cell Therapy Processes

    Dana-Farber Cancer Institute – Boston, Massachusetts, United States

    Postdoctoral Positions – Reproductive Immunology and Pregnancy Biology

    University of California San Francisco – San Francisco, California, United States

    Postdoctoral Research Associate – Oncology

    St. Jude Children’s Research Hospital – Memphis, Tennessee, United States

    > See All Jobs

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