Umbilical & Placental Cell News Volume 15.20 | Jun 1 2023

June 1, 2023

2023-06-01 | UPCN 15.20

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Vol. 15.20 – 1 June, 2023

TOP STORY

Intravenous Injection of Human Umbilical Cord-Derived Mesenchymal Stem Cells Ameliorates Not Only Blood Glucose but Also Nephrotic Complication of Diabetic Rats through Autophagy-Mediated Anti-Senescent Mechanism

Researchers investigated the regulation of placentas and uterus remodeling and involvement of E2 in gestational diabetes mellitus.
[Biology Of Reproduction]

Full Article

PUBLICATIONSRanked by the impact factor of the journal

Exosomes from Human Umbilical Cord Mesenchymal Stem Cells Facilitates Injured Endometrial Restoring in Early Repair Period through miR-202-3p Mediating Formation of ECM

Scientists aimed to investigate the role of hucMSCs-derived exosomal microRNA-202-3p in endometrial damage repair.
[Stem Cell Reviews And Reports]

Abstract Graphical Abstract

Human Wharton’s Jelly Mesenchymal Stem Cells Derived-Exosomes Enriched by miR-124 Promote an Anti-Fibrotic Response in an Experimental Model of Liver Fibrosis

The authors investigated whether delivery of miR-124 through human Wharton’s jelly MSCs derived-exosomes (hWJMSC-Exo) could improve liver fibrosis.
[International Immunopharmacology]

Abstract

Molecular Analysis and Comparison of CD34⁺ and CD133⁺ Very Small Embryonic-Like Stem Cells (VSELs) Purified from Umbilical Cord Blood (UCB)

Researchers performed initial molecular characterization of CD34⁺Lin^–CD45^– and CD133⁺Lin^–CD45^– UCB-derived VSELs populations for expression of selected pluripotency markers and compared these cells at the proteomic level.
[Cytometry Part A]

Abstract

Regulation of Uterus and Placenta Remodeling under High Estradiol Levels in Gestational Diabetes Mellitus Models

Investigators established in vitro and in vivo models for gestational diabetes mellitus placentas by culturing BeWo cells under hyperglycemic concentration, and treating pregnant rats with streptozotocin.
[Stem Cell Research & Therapy]

Abstract
Graphical Abstract

Placental Homing Peptide Guides HIF1α-Silenced Exosomes Conjugates for Targeted Enhancement of Invasion of Trophoblast Cells

Scientists developed a method for targeted delivery of HIF1α‑silenced exosomes to the placenta. HIF1α was overexpressed in JEG‑3 cells.
[Molecular Medicine Reports]

Abstract

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REVIEWS

Application of Mesenchymal Stem Cells (MSCs) in Neurodegenerative Disorders: History, Findings, and Prospective Challenges

The authors compared and contrasted the numerous mesenchymal cell sources and their cellular features. These many sources of mesenchymal cells included adipocyte cells, fetal umbilical cord tissue, and bone marrow.
[Pathology – Research and Practice]

Full Article

INDUSTRY AND POLICY NEWS

UO’s Knight Campus Reveals Design of Second Science Building and New Engineering Program

The University of Oregon’s Knight Campus has released design details of its second science building now under construction. The sprawling facility will enable the evolution of a new bioengineering program at the unviersity.
[Oregon Public Broadcasting]

Press Release

FEATURED EVENT

Umbilical & Placental Cell News Volume 15.20 | Jun 1 2023

Intravenous Injection of Human Umbilical Cord-Derived Mesenchymal Stem Cells Ameliorates Not Only Blood Glucose but Also Nephrotic Complication of Diabetic Rats through Autophagy-Mediated Anti-Senescent Mechanism

Exosomes from Human Umbilical Cord Mesenchymal Stem Cells Facilitates Injured Endometrial Restoring in Early Repair Period through miR-202-3p Mediating Formation of ECM

Human Wharton’s Jelly Mesenchymal Stem Cells Derived-Exosomes Enriched by miR-124 Promote an Anti-Fibrotic Response in an Experimental Model of Liver Fibrosis

Molecular Analysis and Comparison of CD34⁺ and CD133⁺ Very Small Embryonic-Like Stem Cells (VSELs) Purified from Umbilical Cord Blood (UCB)

Regulation of Uterus and Placenta Remodeling under High Estradiol Levels in Gestational Diabetes Mellitus Models

Placental Homing Peptide Guides HIF1α-Silenced Exosomes Conjugates for Targeted Enhancement of Invasion of Trophoblast Cells

Application of Mesenchymal Stem Cells (MSCs) in Neurodegenerative Disorders: History, Findings, and Prospective Challenges

UO’s Knight Campus Reveals Design of Second Science Building and New Engineering Program

Advanced Cell and Tissue Biomanufacturing

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Postdoctoral Research Associate – Bioinformatics & Umbilical Cord Blood

Research Assistant Professor – Obstetrics and Gynecology

PhD Student – Clinical Chemistry and Molecular Diagnostics

Postdoctoral Positions – Reproductive Immunology and Pregnancy Biology

Research Faculty Position – Placental Biology and Gynecologic Oncology

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