Umbilical & Placental Cell News Volume 15.24 | Jun 29 2023

    By
    Laurisa Dohm
    -
    0
    33








    2023-06-29 | UPCN 15.24


    Umbilical-and-Placental-Cell-News-email-header (1)
    Vol. 15.24 – 29 June, 2023
    TOP STORY

    Mesenchymal Stem Cell-Derived Exosomal miR-27b-3p Alleviates Liver Fibrosis via Downregulating YAP/LOXL2 Pathway

    The authors investigated the efficacy and underlying mechanisms of human umbilical cord-derived exosomes in lysyl oxidase-like 2 (LOXL2) inhibition of liver fibrosis.
    [Journal Of Nanobiotechnology]

    Full Article
    Image of man completing the on-demand CFU assay course on his laptop.
    PUBLICATIONSRanked by the impact factor of the journal

    Nanofibrous Polycaprolactone/Amniotic Membrane Facilitates Peripheral Nerve Regeneration by Promoting Macrophage Polarization and Regulating Inflammatory Microenvironment

    A multi-layer multifunctional nanofiber composite membrane of polycaprolactone and amniotic membrane was constructed using electrospinning, and tested in the context of nerve regeneration.
    [International Immunopharmacology]

    AbstractGraphical Abstract

    Potential Role of Human Umbilical Cord Stem Cells-Derived Exosomes As Novel Molecular Inhibitors of Hepatocellular Carcinoma Growth

    Proliferation, apoptosis, and angiogenesis effects were assessed together with the cell viability evaluation by MTT assay in HepG2 cells at 24/48 hours, with or without umbilical cord-MSCs-derived exosomes.
    [Apoptosis]

    Full Article

    Amniotic Fluid-Derived Exosomes Attenuated Fibrotic Changes in POI Rats through Modulation of the TGF-β/Smads Signaling Pathway

    Scientists investigated the regenerative effects of amniotic fluid exosomes in a rat model for premature ovarian insufficiency.
    [Journal Of Ovarian Research]

    Full Article

    Intra-Articular Injection of Secretome, Derived from Umbilical Cord Mesenchymal Stem Cell, Enhances the Regeneration Process of Cartilage in Early-Stage Osteo-Arthritis: An Animal Study

    19 male sheep, which were operated on with total lateral meniscectomy to induce knee osteoarthritis, were divided into three groups: the secretome group, hyaluronic acid group, and MSC group.
    [Acta Orthopaedica]

    Abstract

    Human Umbilical Cord Mesenchymal Stem Cells-Derived Exosomal lncRNA FAM99B Represses Hepatocellular Carcinoma Cell Malignancy

    Investigators explored the effects of human umbilical cord MSC-exosomes carrying lncRNA family with sequence similarity 99-member B FAM99B) on hepatocellular carcinoma cell behavior.
    [Molecular Biotechnology]

    Abstract
    Watch the webinar where Dr. Suzan Imren discusses factors affecting the balance between HSC self-renewal and leukemic transformation
    REVIEWS

    Wharton’s Jelly Mesenchymal Stem Cells: A Concise Review of Their Secretome and Prospective Clinical Applications

    The authors highlight the current advances in research on the Wharton’s jelly-MSCs’ secretome, and its prospective clinical applications.
    [Frontiers In Cell And Developmental Biology]

    Full Article
    INDUSTRY AND POLICY NEWS

    Anthony Nolan Award Winners at Prestigious Ceremony

    Dr. Robert Wynn, Consultant Paediatric Haematologist at the Manchester Children’s Hospital, has won Clinical Supporter of the Year at the Anthony Nolan Supporter Awards 2023 for his exceptional work championing cord blood research.
    [The Hippocratic Post]
    FEATURED EVENT

    Unconventional and Emerging Experimental Organisms in Cell and Developmental Biology

    September 17 – 20, 2023
    Surrey, England, United Kingdom

    > See All Events

    JOB OPPORTUNITIES

    Senior Applications Programmer – Cord Blood Bank Program

    The University of Texas MD Anderson Cancer Center – Houston, Texas, United States

    Research Assistant – ESCs & Placenta

    The University of California San Francisco – San Francisco, California, United States

    Research Faculty Position – Placenta Biology & Gynecology

    The Medical College of Wisconsin – Milwaukee, Wisconsin, United States

    Postdoctoral Research Associate – Bioinformatics & Umbilical Cord Blood

    University of Edinburgh – Edinburgh, Scotland, United Kingdom

    Research Assistant Professor – Obstetrics and Gynecology

    University of Pennsylvania – Philadelphia, Pennsylvania, United States

    > See All Jobs

    Submit an article, publication, job or event
    Brought to you by
    stemcell-logo-for newsletter-2
    Cord Blood News Twitter