Umbilical & Placental Cell News Volume 15.33 | Aug 31 2023

August 31, 2023

2023-08-31 | UPCN 15.33

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Vol. 15.33 – 31 August, 2023

TOP STORY

Combination Human Umbilical Cord Perivascular and Endothelial Colony Forming Cell Therapy for Ischemic Cardiac Injury

The combination of first-trimester human umbilical cord perivascular cells and endothelial colony forming cells synergistically reduced fibrosis and cardiomyocyte apoptosis, while promoting favorable cardiac remodeling and contractility.
[NPJ Regenerative Medicine]

Full Article

STEMCELL has implemented an Environmental Management System that is now ISO 14001-certified.

PUBLICATIONSRanked by the impact factor of the journal

Placenta-Derived Extracellular Vesicles from Preeclamptic Pregnancies Impair Vascular Endothelial Function via Lectin-Like Oxidized LDL Receptor-1

Syncytiotrophoblast-derived extracellular vesicles from preeclampsia placentas were collected by perfusion of placentas from women with preeclampsia and in vitro and ex vivo endothelial cell function were assessed.
[Hypertension]

Abstract

Human Umbilical Cord Mesenchymal Stromal Cell Small Extracellular Vesicle Transfer of microRNA-223-3p to Lung Epithelial Cells Attenuates Inflammation in Acute Lung Injury in Mice

In vitro, A549 cells and primary human small airway epithelial cells were stimulated with LPS with or without human umbilical cord-derived MSC small extracellular vesicles treatment.
[Journal Of Nanobiotechnology]

Full Article

A Novel Therapeutic Management for Diabetes Patients with Chronic Limb-Threatening Ischemia: Comparison of Autologous Bone Marrow Mononuclear Cells Versus Allogenic Wharton Jelly-Derived Mesenchymal Stem Cells

Scientists compared the safety and beneficial therapeutic effect of autologous bone marrow mononuclear cell versus allogeneic Wharton jelly-derived MSCs in diabetic patients with chronic limb-threatening ischemia.
[Stem Cell Research & Therapy]

Full Article

External Application of Human Umbilical Cord-Derived Mesenchymal Stem Cells in Hyaluronic Acid Gel Repairs Foot Wounds of Types I and II Diabetic Rats through Paracrine Action Mode

After analyzing the physical and biological properties of hyaluronic acid (HA) gel, human umbilical cord-derived MSCs-HA gel was applied in two in vivo models, and a molecular mechanism was investigated.
[Stem Cells Translational Medicine]

Full Article Graphical Abstract

Extracellular Vesicles from Human Umbilical Cord Mesenchymal Stem Cells Prevent Steroid-Induced Avascular Necrosis of the Femoral Head via the PI3K/AKT Pathway

The effects of human umbilical cord MSC-extracellular vesicles were assessed by measuring the microstructure of the femoral head using HE staining, micro-computed tomography, and TUNEL staining.
[Food And Chemical Toxicology]

Abstract

Learn how to avoid jargon and use blogs and social media channels to inform the public about your science

REVIEWS

Use of Multiple Doses of Intravenous Infusion of Umbilical Cord-Mesenchymal Stem Cells for the Treatment of Adult Patients with Severe COVID-19-Related Acute Respiratory Distress Syndrome: Literature Review

The authors review the 2020–2022 PubMed literature database concerning the clinical efficacy of intravenous infusion-umbilical cord-MSCs among severe COVID-19 patients.
[Stem Cells International]

Full Article

INDUSTRY AND POLICY NEWS

Stem Cells Used to Successfully Treat Arthritis in Gorilla at Budapest Zoo

Professor Kiss-Tóth and Professor Wilkinson are now jointly leading a preclinical program to test Stem CellX technologies for the development of a similar stem cell treatment in human patients.
[University of Sheffield]

Editorial

FEATURED EVENT

Umbilical & Placental Cell News Volume 15.33 | Aug 31 2023

Combination Human Umbilical Cord Perivascular and Endothelial Colony Forming Cell Therapy for Ischemic Cardiac Injury

Placenta-Derived Extracellular Vesicles from Preeclamptic Pregnancies Impair Vascular Endothelial Function via Lectin-Like Oxidized LDL Receptor-1

Human Umbilical Cord Mesenchymal Stromal Cell Small Extracellular Vesicle Transfer of microRNA-223-3p to Lung Epithelial Cells Attenuates Inflammation in Acute Lung Injury in Mice

A Novel Therapeutic Management for Diabetes Patients with Chronic Limb-Threatening Ischemia: Comparison of Autologous Bone Marrow Mononuclear Cells Versus Allogenic Wharton Jelly-Derived Mesenchymal Stem Cells

External Application of Human Umbilical Cord-Derived Mesenchymal Stem Cells in Hyaluronic Acid Gel Repairs Foot Wounds of Types I and II Diabetic Rats through Paracrine Action Mode

Extracellular Vesicles from Human Umbilical Cord Mesenchymal Stem Cells Prevent Steroid-Induced Avascular Necrosis of the Femoral Head via the PI3K/AKT Pathway

Use of Multiple Doses of Intravenous Infusion of Umbilical Cord-Mesenchymal Stem Cells for the Treatment of Adult Patients with Severe COVID-19-Related Acute Respiratory Distress Syndrome: Literature Review

Stem Cells Used to Successfully Treat Arthritis in Gorilla at Budapest Zoo

Infectious Diseases through an Evolutionary Lens

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Associate – Quality Assurance

Senior Scientist – Stem Cell Engineering

Bioinformatics Scientist – Circulating Trophoblasts Profiling

Postdoctoral Research Fellowship – Toxicology/Pharmacology

Research Laboratory Technician – Organoids & Placentation

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