Umbilical & Placental Cell News Volume 15.34 | Sep 7 2023

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    2023-09-07 | UPCN 15.34


    Umbilical-and-Placental-Cell-News-email-header (1)
    Vol. 15.34 – 7 September, 2023
    TOP STORY

    Versatile Hydrogel Dressings that Dynamically Regulate The Healing of Infected Deep Burn Wounds

    Researchers developed a multifunctional antimicrobial peptide- and placental MSCs-loaded macroporous hydrogel that could fight bacterial infection and regulate wound healing progression by temporally regulating cytokine production by internal stem cells.
    [Advanced Healthcare Materials]

    Abstract
    Explore the Science Events Calendar to discover conferences, podcasts, webinars, and more!
    PUBLICATIONSRanked by the impact factor of the journal

    Umbilical Cord-Derived Mesenchymal Stem Cells Cultured in the MCL Medium for Aplastic Anemia Therapy

    The peripheral blood cell in the aplastic anemia groups was at a low level while that in the MSC group recovered rapidly.
    [Stem Cell Research & Therapy]

    Full Article

    hUMSC Transplantation Restores Follicle Development in Ovary Damaged Mice via Re-Establishment Extracellular Matrix (ECM) Components

    Investigators performed qRT-PCR and IHC to assess the differential expression of selected differentially expressed genes in control, damaged, human umbilical cord MSCs-transplanted and non-transplanted ovaries.
    [Journal Of Ovarian Research]

    Full Article

    Characterization of a Human Placental Clearance System to Regulate Serotonin Levels in the Fetoplacental Unit

    Human placentas from uncomplicated term pregnancies were used for perfusion studies, culturing explants, and isolating primary trophoblast cells.
    [Reproductive Biology And Endocrinology]

    Full Article

    Melatonin-Pretreated HucMSCs Improved Endometrium Regeneration and Fertility Recovery through Macrophage Immunomodulation in Rats with Intrauterine Adhesions

    The authors explored the effect of melatonin on the biological activity of human umbilical cord MSCs in vitro through a macrophage co-culture system, CCK-8, EdU, flow cytometry, immunofluorescence staining, and qRT-PCR.
    [Biology Of Reproduction]

    AbstractGraphical Abstract

    The Role of PGRMC2 in the Trophoblast Invasion

    Scientists discovered that in the first trimester placentas, PGRMC2 was highly expressed in syncytiotrophoblast but significantly lower in extravillous trophoblasts andcytotrophoblasts, indicating a divergent role for PGRMC2 in trophoblast functions.
    [Biology Of Reproduction]

    AbstractGraphical Abstract
    Webinar: The Promise of Organoid Medicine
    REVIEWS

    Creating Mini-Pregnancy Models In Vitro with Clinical Perspectives

    The authors review recent achievements in culturing cells from tissues involved in pregnancy; specifically, trophoblasts from the placenta, and more.
    [Ebiomedicine]

    Full Article
    INDUSTRY AND POLICY NEWS

    UK Finally Rejoins Horizon Europe Research Funding Scheme

    The UK government announced that it will rejoin the European Union’s €95 billion research funding program known as Horizon Europe.
    [ScienceInsider]

    Editorial
    FEATURED EVENT

    Organoids: Modelling Organ Development and Disease in 3D Culture

    October 18 – 21, 2023
    EMBL Heidelberg and Virtual

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    JOB OPPORTUNITIES

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    UT Southwestern Medical Center – Dallas, Texas

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    Amgen – Burnaby, British Columbia, Canada

    Bioinformatics Scientist – Circulating Trophoblasts Profiling

    RareCyte – Seattle, Washington, United States

    Research Associate – Recombinant Protein

    Creative Biolabs – New York, New York, United States

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