Umbilical & Placental Cell News Volume 15.36 | Sep 21 2023

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    2023-09-21 | UPCN 15.36


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    Vol. 15.36 – 21 September, 2023
    TOP STORY

    Successful Cord Blood Transplantation for del7q Myelodysplastic Syndrome in Pearson Marrow Pancreas Syndrome

    Scientists reported successful cord blood transplantation with four years of follow-up for a child with Pearson marrow pancreas syndrome who developed myelodysplastic syndrome with deletion of chromosome 7q (del7q).
    [American Journal Of Hematology]

    Full Article

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    PUBLICATIONSRanked by the impact factor of the journal

    Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Cutaneous Wound Healing in Type 2 Diabetic Mice via Macrophage Pyroptosis Inhibition

    Umbilical cord MSCs were cultured in vitro and apoptosis was induced. ApoEVs were extracted and identified and used in a type 2 diabetes mellitus mouse cutaneous wound model to evaluate their efficacy.
    [Stem Cell Research & Therapy]

    Full Article

    A Novel Multifunctional Chitosan-Gelatin/Carboxymethyl Cellulose-Alginate Bilayer Hydrogel Containing Human Placenta Extract for Accelerating Full-Thickness Wound Healing

    Researchers presented a multifunctional bi-layer hydrogel incorporating human placenta extract (HPE) for accelerating full-thickness wound healing through sustained HPE release, inhibition of bacteria invasion, and promotion of cell proliferation.
    [International Journal Of Biological Macromolecules]

    Abstract

    Management of Retinitis Pigmentosa via Wharton’s Jelly-Derived Mesenchymal Stem Cells or Combination with Magnovision: Three-Year Prospective Results

    Scientists investigated whether the natural progression rate of retinitis pigmentosa could be decreased with subtenon Wharton’s jelly-derived MSC application alone, or combination with Magnovision.
    [Stem Cells Translational Medicine]

    Full Article

    Graphical Abstract

    Human Placenta-Derived Mesenchymal Stem Cells Ameliorate Diabetic Kidney Disease by Modulating the T Helper 17 Cell/ Regulatory T-Cell Balance through the Programmed Death 1 / Programmed Death-Ligand 1 Pathway

    The authors investigated the therapeutic effects and immunomodulatory mechanisms of human placenta-derived MSCs in diabetic kidney disease.
    [Diabetes Obesity & Metabolism]

    Abstract

    IL-1β Stimulated Human Umbilical Cord Mesenchymal Stem Cells Ameliorate Rheumatoid Arthritis via Inducing Apoptosis of Fibroblast-Like Synoviocytes

    TRAIL receptor-Death receptor 4 (DR4), DR5, and lymphocyte function-associated antigen 1 ligand-intercellular adhesion molecule-1 were upregulated in IL-1β-stimulated human fibroblast-like synoviocytes-rheumatoid arthritis.
    [Scientific Reports]

    Full Article
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    REVIEWS

    Impact of Ferroptosis on Preeclampsia: A Review

    The authors explore the new therapeutic target of preeclampsia through oxidative stress in ferroptosis.
    [Biomedicine & Pharmacotherapy]

    Full ArticleGraphical Abstract
    INDUSTRY AND POLICY NEWS

    NIH Upholds Controversial Plan to Step Up Oversight of Foreign Collaborators

    The US biomedical agency tweaked its new policy after an outcry from researchers, but will forge ahead.
    [Nature News]

    Editorial
    FEATURED EVENT

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    October 25 – 28, 2023
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    JOB OPPORTUNITIES

    Postdoctoral Position – Reproductive Biology & Gynecological Disease

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    Faculty and Postdoc Positions – iHuman Institute

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    Research Technician – Placental Function

    Leeds Institute of Medical Research – Leeds, England, United Kingdom

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    UT Southwestern Medical Center – Dallas, Texas

    Senior Scientist – Stem Cell Engineering

    Amgen – Burnaby, British Columbia, Canada

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