Umbilical & Placental Cell News Volume 15.40 | Oct 26 2023

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    2023-10-26 | UPCN 15.40


    Umbilical-and-Placental-Cell-News-email-header (1)
    Vol. 15.40 – 26 October, 2023
    TOP STORY

    Exosomes from Umbilical Cord-Derived Mesenchymal Stem Cells Combined with Gelatin Methacryloyl Inhibit Vein Graft Restenosis by Enhancing Endothelial Functions

    Human umbilical cord MSC-derived exosomes (Exos) were evaluated via transmission electron microscopy and western blotting. hUCMSC-Exos embedded in a photosensitive GelMA hydrogel were applied topically around venous grafts in a rat model of cervical arteriovenous transplantation.
    [Journal Of Nanobiotechnology]

    Full Article
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    PUBLICATIONSRanked by the impact factor of the journal

    Sodium Alginate Hydrogel Integrated with Type III Collagen and Mesenchymal Stem Cell to Promote Endometrium Regeneration and Fertility Restoration

    Composite alginate hydrogel containing recombinant type III collagen (rCo III) and umbilical cord MSCs were developed. rCo III served as a favorable bioactive molecule, displaying that rCo III administration promotes MSCs proliferation, stemness maintenance and migration.
    [International Journal Of Biological Macromolecules]

    Abstract

    Umbilical Cord-Derived Mesenchymal Stem Cells Attenuate S100-Induced Autoimmune Hepatitis via Modulating Th1 and Th17 Cell Responses in Mice

    Bone marrow-derived MSCs could exert an immunosuppression effect to ameliorate the S100-induced autoimmune hepatitis model by inhibiting several proinflammatory cytokines and upregulating of PD-L1 in liver tissue.
    [Stem Cells International]

    Full Article

    Molecular Pathways in Placental-Fetal Development and Disruption

    Investigators evaluated ten diverse pathways involving molecules expressed in the first trimester human placenta based on their relevance to normal fetal development and to the hypothesis of placental-fetal endocrine disruption.
    [Molecular And Cellular Endocrinology]

    Full Article

    Preclinical Assessment of IL-1β Primed Human Umbilical Cord Mesenchymal Stem Cells for Tendon Functional Repair Through TGF-β/IL-10 Signaling

    Tendon-derived stem cells were isolated and characterized. In vitro, the levels of immunoregulatory-related cytokines such as IL-1β, IL-6, IL-10, and TGF-β secreted by 1βUC-MSCs and unprimed umbilical cord-MSCs was measured.
    [Heliyon]

    Full Article

    Islet Like Cells Induced from Umbilical Cord Mesenchymal Stem Cells with Neonatal Bovine Pancreatic Mesenchymal Exosomes for Treatment of Diabetes Mellitus

    Umbilical cord MSCs were induced to β cells with cytokines (CY) and neonatal bovine pancreatic mesenchymal cell exosomes combined with CY.
    [Hormone And Metabolic Research]

    Abstract
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    REVIEWS

    Maternal-Fetal Cross-Talk via the Placenta: Influence on Offspring Development and Metabolism

    The authors discuss the development and functions of the maternal-placental-fetal interface and how cross-talk between these compartments may be a mechanism for in utero programming, focusing on mechanistic target of rapamycin, adiponectin and O-GlcNac transferase signaling.
    [Development]

    Abstract

    Amniotic Membrane Transplantation: Structural and Biological Properties, Tissue Preparation, Application and Clinical Indications

    Scientists provide an up-to-date overview of amniotic membrane transplantation including the structural and biological properties, preparation and application, clinical indications, and commercially available products.
    [Eye]

    Abstract
    INDUSTRY AND POLICY NEWS

    Velico Medical launches Blood Center Education Program with South Texas Blood & Tissue

    Velico Medical announced the launch of its Blood Center Education Program (BCEP) at South Texas Blood & Tissue. Velico’s BCEP is designed to generate deep customer feedback on the commissioning and operational aspects of the FrontlineODPâ„¢ system for spray drying plasma.
    [Velico (PR Newswire)]

    Press Release
    FEATURED EVENT

    Donor Selection & Cell Source Summit

    November 28 – 30, 2023
    San Francisco, California, United States

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    JOB OPPORTUNITIES

    Postdoctoral Researcher – Cancer Immunology and Immunotherapy

    University of Turku – Turku, Finland

    Postdoctoral Associate – Immune Cells in Blood Diseases and GvHD

    Baylor College of Medicine – Houston, Texas, United States

    Licensing Manager – Human Uterus in Pregnancy and Disease

    Centre for Trophoblast Research – Cambridge, England, United Kingdom

    Research Associate – Developmental Biology

    Mount Saint Vincent University – Halifax, Nova Scotia, Canada

    Postdoctoral Research Fellow – Organic Materials for Next Generation Bioelectronic Devices

    The Leibniz Institute of Polymer Research Dresden – Dresden, Germany

    > See All Jobs

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