Umbilical & Placental Cell News Volume 15.41 | Nov 2 2023

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    2023-11-02 | UPCN 15.41


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    Vol. 15.41 – 2 November, 2023
    TOP STORY

    Cell-Based Versus Corticosteroid Injections for Knee Pain in Osteoarthritis: A Randomized Phase III Trial

    Investigators identified the safety and efficacy of cell injections from autologous bone marrow aspirate concentrate, autologous adipose stromal vascular fraction and allogeneic human umbilical cord tissue-derived MSCs, in comparison to corticosteroid injection.
    [Nature Medicine]

    Full Article
    Watch the webinar where Dr. Suzan Imren discusses factors affecting the balance between HSC self-renewal and leukemic transformation
    PUBLICATIONSRanked by the impact factor of the journal

    Bioengineered Skin Constructs Based on Mesenchymal Stromal Cells and Acellular Dermal Matrix Exposed to Inflammatory Microenvironment Releasing Growth Factors Involved in Skin Repair

    Researchers developed a novel method involving physicochemical and enzymatic treatment of cadaveric human skin to obtain human acellular dermal matrix scaffold.
    [Stem Cell Research & Therapy]

    Full Article

    A Predictive Model Combining Clinical Characteristics and Nutritional Risk Factors for Overall Survival after Umbilical Cord Blood Transplantation

    Scientists performed an integrated clinical characteristic and nutritional risk factor analysis and established a predictive model that could be used to identify umbilical cord blood transplantation recipients with poor overall survival. Internal validation was performed by using the bootstrap method with 500 repetitions.
    [Stem Cell Research & Therapy]

    Full Article

    An Increase in Wharton’s Jelly Membrane Osteocompatibility by a Genipin-Cross-Link

    Investigators proposed to use genipin as an efficient cross-linking agent to significantly improve the elasticity and the enzymatical stability of the Wharton’s jelly matrix.
    [International Journal Of Biological Macromolecules]

    AbstractGraphical Abstract

    Human Umbilical Cord Mesenchymal Stem Cells Alleviated TNBS-Induced Colitis in Mice by Restoring the Balance of Intestinal Microbes and Immunoregulation

    The authors assessed the regulatory effects of human umbilical MSCs on the gut microbiota, T lymphocyte subpopulations and related immune cytokines in the trinitrobenzene sulfonic acid-induced inflammatory bowel diseases model.
    [Life Sciences]

    Abstract

    Adipose-Derived Mesenchymal Stem Cells are Ideal for the Cell-Based Treatment of Refractory Wounds: Strong Potential for Angiogenesis

    Researchers compared the heterogeneity of the human MSCs derived from bone marrow umbilical cord, and adipose tissue in accelerating wound healing and promoting angiogenesis and explored the underlying mechanism.
    [Stem Cell Reviews And Reports]

    AbstractGraphical Abstract
    Facts above claims. Three scientists peer reviewed a life science vendor to get to the truth. See for yourself.
    REVIEWS

    Implications of Maternal-Fetal Health on Perinatal Stem Cell Banking

    Scientists describe the current state of banking of gestational tissues and their derived perinatal stem cells, discuss why the changes in birth trends and delivery methods could affect gestational tissue banking practices
    [Gene Therapy]

    Full Article
    INDUSTRY AND POLICY NEWS

    Grant Bolsters Research to Address Rising Maternal Mortality Rates

    The National Institutes of Health has awarded a $4.1 million grant to Vanderbilt University Medical Center and University of California, San Diego to better understand the mechanism behind the association between preeclampsia and other hypertensive disorders of pregnancy and cardiovascular disease.
    [Vanderbilt University]

    Press Release

    Open-Access Reformers Launch Next Bold Publishing Plan

    The group behind the radical open-access initiative Plan S has announced its next big plan to shake up research publishing — and this one could be bolder than the first. It wants all versions of an article and its associated peer-review reports to be published openly from the outset, without authors paying any fees.
    [Nature News]

    Press Release
    FEATURED EVENT

    Cell Bio 2023

    December 2 – 6, 2023
    Boston, Massachusetts, United States

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    JOB OPPORTUNITIES

    Research Assistant – MSC Biofactories

    National University of Singapore – Singapore, Singapore

    Postdoctoral Researcher – Cancer Immunology and Immunotherapy

    University of Turku – Turku, Finland

    Research Associate – Developmental Biology

    Mount Saint Vincent University – Halifax, Nova Scotia, Canada

    Postdoctoral Associate – Immune Cells in Blood Diseases and GvHD

    Baylor College of Medicine – Houston, Texas, United States

    Licensing Manager – Human Uterus in Pregnancy and Disease

    Centre for Trophoblast Research – Cambridge, England, United Kingdom

    > See All Jobs

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