Umbilical & Placental Cell News Volume 15.42 | Nov 9 2023

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    2023-11-10 | UPCN 15.42


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    Vol. 15.42 – 9 November, 2023
    TOP STORY

    Insights into Highly Engraftable Hematopoietic Cells from 27-Year Cryopreserved Umbilical Cord Blood

    Researchers demonstrated that long-term cryopreserved cord blood retained similar numbers of hematopoietic stem and progenitor cells compared with fresh and recently cryopreserved cord blood units.
    [Cell Reports Medicine]

    Full ArticleGraphical Abstract
    Latest updates and debates on mesenchymal stem cells.
    PUBLICATIONSRanked by the impact factor of the journal

    PLGA Nanoparticles Engineering Extracellular Vesicles from Human Umbilical Cord Mesenchymal Stem Cells Ameliorates Polyethylene Particles Induced Periprosthetic Osteolysis

    Scientists demonstrated that human UCMSCs-Exos-encapsulated poly lactic-co-glycolic acid nanoparticles stimulated osteogenic differentiation while inhibiting the generation of reactive oxygen species and subsequent osteoclast differentiation in vitro.
    [Journal Of Nanobiotechnology]

    Full Article

    The Impact of Placental Genomic Risk for Schizophrenia and Birth Asphyxia on Brain Development

    Pregnancy and birth information were obtained from the Medical Birth Registry of Norway. Polygenic risk scores (PRS) from the latest genome-wide association study in schizophrenia were differentiated into placental PRS and non-placental PRS.
    [Translational Psychiatry]

    Full Article

    NOTCH3 Signaling Controls Human Trophoblast Stem Cell Expansion and Differentiation

    Using trophoblast stem cells, trophoblast organoids and primary cytotrophoblasts of early pregnancy, researchers showed that autocrine NOTCH3 signaling controlled human placental expansion and differentiation.
    [Development]

    Abstract

    Human Umbilical Cord Mesenchymal Stem Cells Inhibit Liver Fibrosis via the microRNA-148a-5p/SLIT3 Axis

    The authors elucidated the intrinsic mechanisms underlying the therapeutic effects of human UC-derived-MSCs in liver fibrosis patients.
    [International Immunopharmacology]

    Full Article

    Efficacy and Safety of Allogeneic Umbilical Cord-Derived Mesenchymal Stem Cells for the Treatment of Complex Perianal Fistula in Crohn’s Disease: A Pilot Study

    Researchers evaluated the efficacy and safety of allogeneic umbilical cord-derived MSCs for complex perianal fistula in patients with Crohn’s disease.
    [Current Stem Cell Research & Therapy]

    Full Article
    Request your free copy of the 'Frequencies of Cell Types in Human Peripheral Blood' Wallchart
    REVIEWS

    Mesenchymal Stem Cells Under Epigenetic Control – The Role of Epigenetic Machinery in Fate Decision and Functional Properties

    The authors summarize the current understanding of the role of epigenetic control of MSC differentiation and immunomodulatory properties.
    [Cell Death & Disease]

    Full Article
    INDUSTRY AND POLICY NEWS

    ISSCR and Cell Press Renew Publishing Agreement for Stem Cell Reports

    The International Society for Stem Cell Research (ISSCR) and publisher Cell Press are extending their partnership to publish the ISSCR’s open access, peer-reviewed journal, Stem Cell Reports.
    [International Society for Stem Cell Research]

    Press Release

    ‘We Need More Women,’ Says Only Female Winner of Millennium Technology Prize

    As a Nobel laureate, Prof Frances Arnold is not short of accolades. Yet being the only woman to so far win the Millennium Technology Prize – the Nobel equivalent for engineers – is one of the least appealing.
    [The Guardian]

    Press Release
    FEATURED EVENT

    Vienna International Symposium

    December 4 – 6, 2023
    Vienna, Austria

    > See All Events

    JOB OPPORTUNITIES

    Laboratory Director – Biobank

    Baylor College of Medicine – Houston, Texas, United States

    Research Assistant – MSC Biofactories

    National University of Singapore – Singapore, Singapore

    Postdoctoral Researcher – Cancer Immunology and Immunotherapy

    University of Turku – Turku, Finland

    Research Associate – Developmental Biology

    Mount Saint Vincent University – Halifax, Nova Scotia, Canada

    Postdoctoral Associate – Immune Cells in Blood Diseases and GvHD

    Baylor College of Medicine – Houston, Texas, United States

    > See All Jobs

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