Umbilical & Placental Cell News Volume 16.04 | Feb 1 2024

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    2024-02-01 | UPCN 16.04


    Umbilical-and-Placental-Cell-News-email-header (1)
    Vol. 16.04 – 1 February, 2024
    TOP STORY

    Mesenchymal Stem Cell Derived Exosomes Repair Uterine Injury by Targeting Transforming Growth Factor-β Signaling

    The authors demonstrated that exosomes derived from placental MSCs could restore uterine functions and improve the fertility rate of injured animals.
    [ACS Nano]

    AbstractGraphical Abstract
    Learn about MSC markers, immune cell interactions, and differentiation methods with this free wallchart.
    PUBLICATIONSRanked by the impact factor of the journal

    Platelet-Rich Plasma-Derived Exosomes Boost Mesenchymal Stem Cells to Promote Peripheral Nerve Regeneration

    Scientists isolated platelet-rich plasma-derived exosomes, which contained abundant bioactive molecules, and investigated their potential to increase the regenerative capacity of MSCs.
    [Journal Of Controlled Release]

    Abstract

    Dysregulated lncRNAs Regulate Human Umbilical Cord Mesenchymal Stem Cell Differentiation into Insulin-Producing Cells by Forming a Regulatory Network with mRNAs

    Human umbilical cord (HUC) MSCs isolated from newborns were progressively induced into insulin-producing cells using small molecules. HUC-MSC and four induced stage samples were prepared.
    [Stem Cell Research & Therapy]

    Full Article

    Human Umbilical Cord Mesenchymal Stem Cells Improve Lung Function in Chronic Obstructive Pulmonary Disease Rat Model through Regulating Lung Microbiota

    The administration of umbilical cord-MSCs in rats led to a progressive amelioration of chronic obstructive pulmonary disease, as demonstrated by enhanced lung function and reduced inflammatory response.
    [Stem Cells]

    Abstract

    Potential Impact on Using Aspirin as the Primary Prevention of Adverse Pregnancy Outcomes in Twins Conceived Using ART

    Scientists retrospectively analyzed 665 twin pregnancies from assisted reproduction technology, grouped according to aspirin use, and followed pregnancy outcomes to assess bleeding risk. Low-dose aspirin was found to be effective in preventing preeclampsia without a significant risk of bleeding.
    [Scientific Reports]

    Full Article

    Human Umbilical Cord Mesenchymal Stem Cells Protect against Ferroptosis in Acute Liver Failure through the IGF1-Hepcidin-FPN1 Axis and Inhibiting Iron Loading

    Researchers investigated the positive effects of MSCs against ferroptosis in an acute liver failure model and explore the underlying molecular mechanisms of their therapeutic function.
    [Acta Biochimica Et Biophysica Sinica]

    Full ArticleGraphical Abstract

    Effect of Human Umbilical Cord Blood-Mesenchymal Stem Cells on Cisplatin-Induced Nephrotoxicity in Rats

    The authors investigated the effect of human umbilical cord blood-MSCs on the histological structure, the oxidant stress, and the inflammatory gene expression in an experimental model of cisplatin-induced nephrotoxicity in rats.
    [Molecular Biology Reports]

    Abstract
    Request a free copy of this wallchart on mouse HSPC subsets, including their frequencies and phenotypes.
    REVIEWS

    Exposure to Microplastics and Human Reproductive Outcomes: A Systematic Review

    Investigators synthesize evidence for the presence of microplastics in human reproductive tissue and their associations with environmental exposures and reproductive outcomes.
    [BJOG-An International Journal Of Obstetrics And Gynaecology]

    Full Article
    INDUSTRY AND POLICY NEWS

    International Space Station Welcomes Trio of Experiments Focused on Enhancing Life Beyond Earth

    NASA’s Biological and Physical Sciences Division is sending three physical sciences and space biology experiments and equipment to the International Space Station aboard Northrop Grumman’s 20th commercial resupply services mission.
    [NASA]

    Full Article
    FEATURED EVENT

    GvHGvL Meeting 2024

    March 13 – 15, 2024
    Erlangen, Germany

    > See All Events

    JOB OPPORTUNITIES

    Research Associate – Maternal & Fetal Health

    The University of Manchester – Manchester, England, United Kingdom

    Faculty Positions – Obstetrics, Gynecology, and Reproductive Health

    Rutgers, New Jersey Medical School – Newark, New Jersey, United States

    Technician – Tissue and Organoid Biobanking

    Human Technopole – Milan, Italy

    PhD Studentship – Key Drivers of Placental Evolution

    University of Southampton – Southampton, England, United Kingdom

    Principal Investigators – Human Cell Lineage Atlas Facility

    Guangzhou Institutes of Biomedicine and Health – Guangzhou, China

    > See All Jobs

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