 | | Vol. 16.08 – 29 February, 2024 |
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| The authors found that fibulin (FBLN) 1 promoted osteogenic differentiation of MSCs and MSC-mediated bone regeneration. It was shown that there was an m6A methylation site in 3′UTR of FBLN1 mRNA, and the mutation of the m6A site enhanced the stability of FBLN1 mRNA.
[Cell Proliferation] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists described the establishment of the first clinical-grade iPSC lines from umbilical cord MSCs in Brazil.
[Stem Cells Translational Medicine] |
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| The feasibility of transitioning was evaluated from an established Wharton’s jelly MSCs 2D production strategy to a new one with stirred-tank bioreactors.
[Biotechnology Journal] |
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| The rat model of acute liver failure (ALF) was induced by D-galactosamine, and human umbilical cord MSCs were administered via the tail vein 12 hours before or 2 hours after induction.
[International Immunopharmacology] |
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| Through comprehensive mapping of H3K4me3, H3K27me3, H3K9me3, and H3K27ac loci during the differentiation of trophoblast stem cells into syncytiotrophoblasts and extravillous trophoblasts, the authors revealed dynamic reconfiguration in H3K4me3 and H3K27ac patterns.
[Scientific Reports] |
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| Investigators retrospectively analyzed the prevalence of anemia, transfusion requirements and outcome in women with placenta accreta spectrum. Using data from the German Statistical Office pregnant patients with deliveries hospitalized between January 2012 and December 2021 were included.
[Scientific Reports] |
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| Researchers evaluated the impact of decellularization on the human amniotic membrane based on its proteome profile, physicochemical features, as well as the attachment, viability, and proliferation of umbilical cord-derived MSCs.
[Journal Of Biomedical Materials Research Part A] |
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| Scientists developed methodologies to extract solid materials from human tissue samples by saponification and ultracentrifugation, allowing for highly specific and quantitative analysis of plastics by pyrolysis-gas chromatography and mass spectrometry
[Toxicological Sciences] |
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| Frozen T cell-free cord blood mononuclear cells were cultured with recombinant human interleukin (rhIL)-18 and rhIL-2 in anti-NKp46 and anti-CD16 antibody immobilization settings.
[Regenerative Therapy] |
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| The authors summarize the apoptosis, necroptosis, and autophagy play both promoting and inhibiting roles in the differentiation, invasion of trophoblast, remodeling of the uterine spiral artery and decidualization, whereas ferroptosis and pyroptosis have adverse effects.
[Cell Death Discovery] |
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| Scientists evaluated the effectiveness of growth factor gene-modified stem cells in restoring motor function after spinal cord injury. They searched four databases, including PubMed, Embase, Web of Science, and Scopus, to identify relevant records.
[Neurosurgical Review] |
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| The University of California, Irvine (UCI) received a five-year, $4 million grant from the California Institute for Regenerative Medicine to establish a shared resources lab in the Sue & Bill Gross Stem Cell Research Center.
[UCI News] |
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| | University of Sydney – Sydney, Australia |
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| | University of Alberta – Edmonton, Alberta, Canada |
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| | University of Amsterdam – Amsterdam, Netherlands |
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| | University of Maryland Baltimore – Baltimore, Maryland, United States |
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| | Rutgers, New Jersey Medical School – Newark, New Jersey, United States |
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