Tim-3⁺ Decidual Mφs Induced Th2 and Treg Bias in Decidual CD4⁺ T Cells and Promoted Pregnancy Maintenance via CD132

Investigators found the higher frequency of Tim-3+ decidual macrophages (Mφs) in response to trophoblasts. The reduced abundance of Tim-3 on Mφs was accompanied by disordered anti- and pro-inflammatory cytokine profiles in miscarriage.