NewslettersMammary Cell NewsTranscriptional Repression by FoxM1 Suppresses Tumor Differentiation and Promotes Metastasis of Breast CancerBy Bob - May 19, 20220376Using CRISPR-Cas9 engineering, investigators generated a mouse model that expressed Forkhead box M1 (FoxM1) harboring point mutations that blocked binding to Rb while retaining its ability to bind CREB-binding protein.[Cancer Research]Abstract