HDL-Mediated Reduction of Cholesterol Content Inhibits the Proliferation of Prostate Cancer Cells Induced by LDL: Role of ABCA1 and Proteasome Inhibition

Scientists investigated the ability of high-density lipoproteins (HDL) to modulate cholesterol content and metabolism in androgen receptor (AR)-positive and AR-null prostate cancer cell lines and the consequences on cell proliferation.