Application of Box-Behnken Design for Optimization of Phenolics Extraction from Leontodon hispidulus in Relation to Its Antioxidant, Anti-inflammatory and Cytotoxic Activities

Antioxidant, anticancer and anti-inflammatory activities were evaluated by ABTS-assay, prostate and cervical carcinoma human cell lines and carrageenan-induced rat paw edema model, respectively.