Schlafen2 Is a Regulator of Quiescence in Adult Murine Hematopoietic Stem Cells

To investigate the role of schlafen2 (Slfn2) in the regulation of HSCs, scientists studied HSC function in the elektra mouse model, where the elektra allele of the Slfn2 gene contained a point mutation causing loss of function of the Slfn2 protein.