Chondroitin Sulfate Proteoglycans Prevent Immune Cell Phenotypic Conversion and Inflammation Resolution via TLR4 in Rodent Models of Spinal Cord Injury

Researchers revealed that chondroitin sulfate proteoglycans played a critical role in preventing inflammation resolution by blocking the conversion of pro-inflammatory immune cells to a pro-repair phenotype in rodent models of spinal cord injury.