NewslettersHematopoiesis NewsPLAG1 Dampens Protein Synthesis to Promote Human Hematopoietic Stem Cell Self-RenewalBy Danielle Corrigan - June 7, 20220527The authors demonstrated that the transcription factor PLAG1 was essential for long-term HSC function and when overexpressed endowed a 15.6-fold enhancement in the frequency of functional HSC in stimulatory conditions.[Blood]Full Article