Nuclear p120 Catenin Is a Component of the Perichromosomal Layer and Coordinates Sister Chromatid Segregation During Mitosis in Lung Cancer Cells

The dynamic changes in nuclear p120 catenin localization during cell cycle progression were investigated. Scientists validated the role of nuclear p120 catenin in the formation of the chromosome periphery and revealed the p120 catenin-lumican interaction may have coupled orientation of cell division with the segregation of sister chromatids during mitosis.