Steroid Nuclear Receptor Coactivator 2 Controls Immune Tolerance by Promoting Induced Treg Differentiation via Up-Regulating Nr4a2

Steroid nuclear receptor coactivator 2 (SRC2) was dispensable for the development of thymic Tregs, whereas naive CD4+ T cells from mice deficient of SRC2 specific in Tregs displayed defective Treg differentiation.