Targeting Autophagy as a Therapeutic Strategy against Pancreatic Cancer

Given the multifaceted and context-dependent roles of autophagy in both cancer cells and normal host cells, a deeper understanding of the mechanisms underlying the tumor-promoting roles of autophagy as well as of the consequences of autophagy inhibition is necessary for the development of autophagy inhibition-based therapies against PDAC.
[Journal of Gastroenterology]
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