Review

[Seminars In Cancer Biology] The authors summarize the phenotypic and functional features of exhaust and senescent T cells, and describes the key drivers of the two T cell dysfunctional states in the tumor microenvironment and their functional roles in ovarian cancer.

[Medical Oncology] The authors explore the various functions of exosomes in colorectal cancer and their potential as diagnostic markers, therapeutic targets, and drug delivery vehicles.

[Neoplasia] Given the need for novel approaches to treat PCa (prostate cancer), there is significant interest in new therapies that target m6A that modulate androgen receptor expression and androgen signaling. This review critically summarizes the potential benefit of such epitranscriptomic therapies for PCa patients.

[Cancer Letters] The authors review the establishment of tumor organoid models and provide an extensive overview of organoid culturing strategies.

[Biomedicine & Pharmacotherapy] Investigators discuss liver and bile duct organoids with special emphasis on tumoroids and their applications, advantages, and shortcomings.

Investigators discuss how prior or concomitant treatment with an antiangiogenic drug can improve CAR T cell therapy, to become an attractive strategy for the treatment of solid tumors.