3D Tumor Angiogenesis Models: Recent Advances and Challenges

Scientists summarize recent advancements of 3D tumor vascular model systems which include tissue engineering-based tumor models; vascular organoid models, and organ-on-chips and their importance in replicating the tumor angiogenesis along with the associated challenges to design improved models.
[Journal of Cancer Research and Clinical Oncology]
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Nutraceuticals and Their Role in Tumor Angiogenesis

The literature concerning the pro-angiogenic and/or anti-angiogenic nutraceuticals and the possible activated pathways in cancer and other non-neoplastic diseases by in vivo and in vitro experiments are reviewed.
[Experimental Cell Research]
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Control of Host Mitochondria by Bacterial Pathogens

The authors discuss nonimmunological pathogenic mechanisms that converge on the ability of bacteria to control the mitochondrial compartment of host cells.
[Trends in Microbiology]
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Bioinspired and Biomimetic Delivery Platforms for Cancer Vaccines

Recent advances in bioinspired delivery platforms for cancer vaccines, existing obstacles faced, as well as insights and future directions for the field are discussed.
[Advanced Materials]
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Current Status of Organoid Culture in Urological Malignancy

The authors summarize the development and applications of three-dimensional organoid cultures in urological cancers, mainly focusing on prostate, urinary bladder and kidney cancers, and assess the future prospects of this model.
[International Journal of Urology]
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Building and Maintaining the Skin

Investigators review diverse cellular interactions and highlight how far-reaching signals can be transmitted at the local level to enable skin stem cells to tailor their actions to suit the particular occasion and optimize fitness.
[Cold Spring Harbor Perspectives in Biology]
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Insight into the Role of Dermal White Adipose Tissue Loss in Dermal Fibrosis

The authors indicate that the adipocytes-to-myofibroblasts transition in dermal white adipose tissue reflects the direct contribution to the dermal fibrosis formation
[Journal of Cellular Physiology]
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LINC00662: A New Oncogenic lncRNA with Great Potential

LINC00662 can reduce the promoter methylation level of s-adenosylmethionine-dependent hepatocellular carcinoma-promoting genes by regulating the MAT1A/SAM and AHCY/SAH axes, thereby promoting the activation of oncogenes. Scientists summarize the molecular regulation mechanism of LINC00662.
[Journal of Cellular Physiology]
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Foresight regarding Drug Candidates Acting on the Succinate–GPR91 Signaling Pathway for Non-Alcoholic Steatohepatitis (Nash) Treatment

The authors describe the mechanism of the succinate–GPR91 signaling pathway in NASH and summarize the drugs that act on this pathway, with the aim of providing a new approach to NASH treatment.
[Biomedicine & Pharmacotherapy]
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A Comprehensive Review of the Impact of Obesity on Plasma Cell Disorders

Researchers provide a detailed summary of what is known about the impact of obesity on the pathogenesis of multiple myeloma (MM), its influence on outcomes in MM patients, and discuss potential mechanisms through which obesity is postulated to influence MM risk and prognosis.
[Leukemia]
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Retinoic Acid Signaling in Heart Development: Application in the Differentiation of Cardiovascular Lineages from Human Pluripotent Stem Cells

Scientists discuss the role of retinoic acid (RA) in cardiogenesis, currently available protocols that employ RA for differentiation of various cardiovascular lineages, and plausible transcriptional mechanisms underlying this fate specification.
[Stem Cell Reports]
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