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Native and Engineered Extracellular Vesicles: Novel Tools for Treating Liver Disease

[Journal Of Materials Chemistry B] The authors introduce the mechanisms and effects of native extracellular vesicles derived from different cells and tissues to treat liver diseases of different etiologies.

Regulatory Role of CD39 and CD73 in Tumor Immunity

[Future Oncology] Investigators focus on the role of CD39 and CD73 in immune response and malignant progression, including the expression of CD39 within the tumor microenvironment and its relationship to immune effector cells, and its role in antigen presentation.

B Cells and Atherosclerosis: A HIV Perspective

[Journal of Cellular Physiology] The authors review the multifaceted functions of B cells in atherosclerosis, with a specific focus on HIV. Unique to atherosclerosis is the pivotal role of natural antibodies, particularly those targeting oxidized epitopes abundant in modified lipoproteins and cellular debris.

From Stem Cells to Pancreatic β-Cells: Strategies, Applications, and Potential Treatments for Diabetes

[Molecular And Cellular Biochemistry] Scientists introduce the development of functional β-cells and their heterogeneity and then turn to highlight recent advances in the generation of β-cells from stem cells and their potential applications in disease modeling, drug discovery and clinical therapy.

Replacing Animal Testing With Stem Cell-Organoids: Advantages and Limitations

[Stem Cell Reviews And Reports] Scientists focused on stem cell related methodologies, such as organoids, that could serve as an alternative to animal testing and discuss its advantages and limitations, alongside regulatory considerations.

miR-192 Family in Breast Cancer: Regulatory Mechanisms and Diagnostic Value

[Biomedicine & Pharmacotherapy] The authors describe the regulatory mechanism of the miRNA-192 family affecting the malignant behavior of breast cancer cells and evaluate the value of the miRNA-192 family as a diagnostic and prognostic biomarker for breast cancer.

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