Blocking CDK7-Mediated NOTCH1-cMYC Signaling Attenuates Cancer Stem Cell Activity in Anaplastic Thyroid Cancer

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To determine the regulatory action of NOTCH1-cMYC signaling in CSC maintenance, scientists evaluated the effect of a selective NOTCH1 inhibitor, crenigacestat, on CSC capacities in anaplastic thyroid cancer
[Thyroid]
Abstract