CRISPR Interference Interrogation of COPD GWAS Genes Reveals the Functional Significance of Desmoplakin in iPSC-Derived Alveolar Epithelial Cells

By
Danielle Corrigan
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0
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The authors applied CRISPR interference to interrogate the function of nine genes implicated in COPD by genome-wide association studies in induced pluripotent stem cell–derived type 2 alveolar epithelial cells.
[Science Advances]
Abstract