Snail Acetylation by Autophagy-Derived Acetyl-Coenzyme a Promotes Invasion and Metastasis of KRAS-LKB1 Co-Mutated Lung Cancer Cells

Researchers employed a liquid chromatography-based metabolomic approach with kirsten rat sarcoma viral oncogene (KRAS) and liver kinase B1 (LKB1) gene co-mutated cells that represented an autophagy/epithelial-to-mesenchymal transition (EMT)-coactivated invasive lung cancer subtype for the identification of metabolites linked to autophagy-driven EMT activation.