MicroRNA-497 Prevents Pancreatic Cancer Stem Cell Gemcitabine Resistance, Migration, and Invasion by Directly Targeting Nuclear Factor Kappa B 1

Researchers demonstrated that overexpression of nuclear factor kappa B 1 (NFκB1) could promote the viability, migration, and invasion of gemcitabine-treated pancreatic cancer stem cells, but this effect could be partially abolished by miR-497 overexpression.